Supported by National Institute on Aging

Illustrations of Amyloid Fibril structures deposited in the Protein Data Bank. Click on thumbnails below to see high resolution images of the amyloid fibril colored by residue or energy.
See our accompanying review: The expanding amyloid family: Structure, stability, function, and pathogenesis, Cell, Vol 184, Issue 19, Sept. 16, 2021, pp. 4857-4873

	Protein Information	Polarity Map	Energy Map
1 △	Amyloid-β(1-40) Paravastu et al., 2008 Human, recombinant, positive stagger fibril 2lmn ssNMR residues:9-40 resolution:0
2 △	Amyloid-β(1-40) Paravastu et al., 2008 Human, recombinant, negative stagger fibril 2lmo ssNMR residues:9-40 resolution:0
3 △	Amyloid-β(1-40) Paravastu et al., 2008 Human, recombinant, positive stagger fibril 2lmp ssNMR residues:9-40 resolution:0
4 △	Amyloid-β(1-40) Paravastu et al., 2008 Human, recombinant, negative stagger fibril 2lmq ssNMR residues:9-40 resolution:0
5 △	Amyloid-β(1-40) Lu et al., 2013 Human, recombinant, seeded from Alzheimers Disease patient brain 2m4j ssNMR residues:1-40 resolution:0
6 △	Amyloid-β(1-40) Kollmer et al., 2019 Human, extracted from Alzheimers Disease patient brain, meningeal tissue 6shs cryoEM residues:1-40 resolution:4.4
7 △	Amyloid-β(1-40) Cerofolini et al., 2020 Human, recombinant 6ti5 ssNMR residues:11-40 resolution:0
8 △	Amyloid-β(1-40) Ghosh et al., 2021 Human, recombinant, seeded with fibrils extracted Alzheimers Disease patient brain, cortical tissue 6w0o cryoEM residues:10-40 resolution:2.77
9 △	Amyloid-β(1-40) Pfeiffer et al., 2023 Human, recombinant, unseeded, morphology i 8ot1 CryoEM residues:13-40 resolution:2.59
10 △	Amyloid-β(1-40) Pfeiffer et al., 2023 Human, recombinant, unseeded, morphology ii 8ot3 CryoEM residues:13-40 resolution:2.73
11 △	Amyloid-β(1-40) Pfeiffer et al., 2023 Human, recombinant, seeded with meningeal tissue of Alzheimer's patients, morphology I 8ot4 CryoEM residues:1-37 resolution:2.59
12 △	Amyloid-β(1-40) and Amyloid-β(1-42) co-fibril Cerofolini et al., 2020 Human, recombinant 6ti6 ssNMR residues:11-40, 11-42 resolution:0
13 △	Amyloid-β(1-40) D23N, Iowa Mutation Qiang et al., 2012 Human, recombinant 2lnq ssNMR residues:15-40 resolution:0
14 △	Amyloid-β(1-40) D23N, Iowa Mutation Sgourakis et al., 2015 Human, recombinant 2mpz ssNMR residues:15-40 resolution:0
15 △	Amyloid-β(1-40) E22G, Arctic mutation Yang et al., 2023 Human, extracted from Alzheimer's patient brain 8bg0 CryoEM residues:11-40 resolution:1.99
16 △	Amyloid-β(1-40) E22G, Arctic mutation Yang et al., 2023 Human, extracted from Alzheimer's mouse model brain 8bg9 CryoEM residues:1-37 resolution:3.5
17 △	Amyloid-β(1-40) E22Δ, Osaka mutation Schütz et al., 2015 Human, recombinant 2mvx ssNMR residues:1-40 resolution:0
18 △	Amyloid-β(1-42) Lührs et al., 2005 Human, recombinant 2beg ssNMR residues:17-42 resolution:0
19 △	Amyloid-β(1-42) Xiao et al., 2015 Human, recombinant 2mxu ssNMR residues:11-42 resolution:0
20 △	Amyloid-β(1-42) Wälti et al., 2016 Human, recombinant 2nao ssNMR residues:14-42 resolution:0
	Protein Information	Polarity Map	Energy Map
21 △	Amyloid-β(1-42) Schmidt et al., 2015 Human, recombinant 5aef CryoEM residues:16-40 resolution:5
22 △	Amyloid-β(1-42) Colvin et al., 2016 Human, recombinant 5kk3 ssNMR residues:14-42 resolution:0
23 △	Amyloid-β(1-42) Gremer et al., 2017 Human, recombinant 5oqv cryoEM residues:1-42 resolution:4
24 △	Amyloid-β(1-42) Liu et al., 2021 Human, synthetic, glycosylated at Tyr10 7f29 CryoEM residues:6-42 resolution:3.1
25 △	Amyloid-β(1-42) Yang et al., 2021 Human, extracted from Alzheimers Disease patient brain, Type 1 fibrils 7q4b CryoEM residues:9-42 resolution:2.5
26 △	Amyloid-β(1-42) Yang et al., 2021 Human, extracted from Alzheimers Disease patient brain, Type 2 fibrils 7q4m CryoEM residues:12-42 resolution:2.8
27 △	Amyloid-β(1-42) Stern et al., 2023 Human, aqueous extract from Alzheimers Disease patient brain, Type 1 fibrils 8azs CryoEM residues:9-42 resolution:2.9
28 △	Amyloid-β(1-42) Stern et al., 2023 Human, aqueous extracts from the brain of a patient with Alzheimers Disease, type II filaments 8azt CryoEM residues:12-42 resolution:3.7
29 △	Amyloid-β(1-42) Lee et al., 2023 Human, recombinant, seeded from the brain of a human with Alzheimers Disease, type A fibril 8ezd CryoEM residues:12-42 resolution:2.83
30 △	Amyloid-β(1-42) Lee et al., 2023 Human, recombinant, seeded from the brain of a human with Alzheimers Disease 8eze CryoEM residues:1-42 resolution:2.76
31 △	Amyloid-β(1-42) E22G, Arctic mutation Leistner et al., 2023 Human, extracted from AppNL-G-F familial AD mouse model brain 8bfa CryoEM residues:1-38 resolution:3
32 △	Amyloid-β(1-42) E22G, Arctic mutation Leistner et al., 2023 Human, extracted from AppNL-G-F familial AD mouse model brain, and stained with methoxy-X04 8bfb CryoEM residues:1-38 resolution:3.2
33 △	Amyloid-β(1-42) E22G, Arctic mutation Yang et al., 2023 Human, extracted from Alzheimers Patient Brain 8bfz CryoEM residues:12-42 resolution:2.8
34 △	Amyloid-β(20-34) Warmack et al., 2019 Human, synthetic 6oiz MicroED residues:20-34 resolution:1.1
35 △	Amyloid-β(20-34)(L-isoAsp23) Warmack et al., 2019 Human, synthetic 6nb9 MicroED residues:20-34 resolution:1.1
36 △	Antibody Light Chain λ1 Radamaker et al., 2019 Human, extracted from cardiac AL amyloidosis patient heart 6ic3 cryoEM residues:15-105 resolution:4
37 △	Antibody Light Chain λ1 Radamaker et al., 2021 Extracted from heart of a patient with systemic AL amyloidosis 7nsl CryoEM residues:9-52, 68-108 resolution:3.1
38 △	Antibody Light Chain λ3 Radamaker et al., 2021 Human, extracted from cardiac AL amyloidosis patient heart, fibril conformation B 6z1i cryoEM residues:9-49, 68-107 resolution:3.4
39 △	Antibody Light Chain λ3 Radamaker et al., 2021 Human, extracted from cardiac AL amyloidosis patient heart, fibril conformation A 6z1o cryoEM residues:9-49, 60-107 resolution:3.2
40 △	Antibody Light Chain λ6 Swuec et al., 2019 Human, extracted from amyloid cardiomyopathy patient heart 6hud cryoEM residues:1-37, 66-105 resolution:3.3
	Protein Information	Polarity Map	Energy Map
41 △	Antibody Light Chain λ6 Puri et al., 2023 Human, extracted from AL amyloidosis patient kidney 8cpe CryoEM residues:1-37, 66-105 resolution:4
42 △	Antimicrobial peptide aurein 3.3 Bücker et al., 2022 Blue-thighed tree frog, synthetic 7qv6 CryoEM residues:1-17 resolution:3.5
43 △	Antimicrobial peptide uperin 3.5 Bücker et al., 2022 Mjobergs toadlet, synthetic 7qv5 CryoEM residues:1-17 resolution:3
44 △	CA150 WW2 Domain Ferguson et al., 2006 Human, recombinant 2nnt ssNMR residues:3-33 resolution:0
45 △	De novo, Biphenyl-4-peptidyl-ffsy D-peptide Guo et al., 2023 Synthetic, induces cells to form spheroids 8fof CryoEM residues:1-5 resolution:2.6
46 △	De novo, Catalytic Amyloid Fibril, Ac-LHLHLRL-NH2, p-nitrophenyl hydrolase Heerde et al., 2023 Synthetic 8b3a CryoEM residues:1-7 resolution:3.8
47 △	De novo, Enzyme-cleaved Amyloid Peptide (EAP2) Wang et al., 2023 synthetic, abeta-2, GPLGMLGGVVIA, polymorph 1 8gz8 CryoEM residues:1-12 resolution:2.35
48 △	De novo, Enzyme-cleaved Amyloid Peptide (EAP2) Wang et al., 2023 synthetic, abeta-2, GPLGMLGGVVIA, polymorph 2 8gz9 CryoEM residues:1-12 resolution:2.62
49 △	De novo, Nitrobenzoxadiazole-ffsy D-peptide Guo et al., 2023 Synthetic, class 1 fibril, induces cells to form spheroids 7t6e CryoEM residues:1-5 resolution:3.1
50 △	De novo, Nitrobenzoxadiazole-ffsy D-peptide Guo et al., 2023 Synthetic, class 2 fibril, induces cells to form spheroids 8dst CryoEM residues:1-5 resolution:3.2
51 △	De novo, Pyrene IDP Guo et al., 2023 synthetic, intrinsically disordered short peptide forms fibrils 7uuq CryoEM residues:1-6 resolution:3.1
52 △	De novo, Pyrene IDP Guo et al., 2023 Synthetic, intrinsically disordered short peptide forms fibrils, pH 4.0, 2mM Ca2+ 8gi5 CryoEM residues:1-6 resolution:3
53 △	De novo, Virus Enhancing Amyloid Fibril, PNF-18, CKFKFQF Heerde et al., 2023 Synthetic 8okr CryoEM residues:1-7 resolution:2.86
54 △	FUS LC Domain Murray et al., 2017 Human, recombinant 5w3n ssNMR residues:37-97 resolution:0
55 △	FUS LC Domain Lee et al., 2021 Human, recombinant 6xfm cryoEM residues:112-150 resolution:2.62
56 △	FUS LC Domain Sun et al., 2021 Human, recombinant 7vqq CryoEM residues:34-124 resolution:2.9
57 △	Glucagon Gelenter et al., 2019 human, synthetic 6nzn ssNMR residues:1-29 resolution:0
58 △	Glucagon Jeong et al., 2022 biorxiv human, synthetic 7xm8 CryoEM residues:1-29 resolution:3.9
59 △	HET-s (218-289) Wasmer et al., 2008 Fungal, Podospora anserina, recombinant 2rnm ssNMR residues:224-283 resolution:0
60 △	hnRNPA1 Sharma et al., 2023 Human, recombinant 7zj2 CryoEM residues:251-295 resolution:3.32
	Protein Information	Polarity Map	Energy Map
61 △	hnRNPA1 (186-320) Sun et al., 2020 Human, recombinant 7bx7 cryoEM residues:251-295 resolution:2.8
62 △	hnRNPA2 Lu et al., 2020 Human, recombinant 6wqk cryoEM residues:251-295 resolution:3.1
63 △	hnRNPA2 D290V mutation Lu et al., 2023 Human, recombinant, fibril polymorph PM1 8du2 CryoEM residues:263-316 resolution:3.3
64 △	hnRNPA2 D290V mutation Lu et al., 2023 Human, recombinant, fibril polymorph PM2 8duw CryoEM residues:263-316 resolution:3.2
65 △	hnRNPA2 D290V mutation Lu et al., 2023 Human, recombinant, fibril polymorph PM3 8ec7 CryoEM residues:263-313 resolution:3.9
66 △	hnRNPDL-2 Garcia-Pardo et al., 2023 Human, recombinant 7zir CryoEM residues:345-395 resolution:2.5
67 △	Insulin Wang et al., 2023 human, recombinant, pH 2, fibril type II 8sbd CryoEM residues:2-20 resolution:3.2
68 △	Islet Amyloid Polypeptide (IAPP) Cao et al., 2020 Human, recombinant, SUMO-tagged 6vw2 cryoEM residues:14-37 resolution:3.7
69 △	Islet Amyloid Polypeptide (IAPP) Röder et al., 2020 Human, synthetic, C-term amidated 6y1a cryoEM residues:13-37 resolution:4.2
70 △	Islet Amyloid Polypeptide (IAPP) Gallardo et al., 2020 Human, synthetic, C-term amidated 6zrf cryoEM residues:13-37 resolution:3.6
71 △	Islet Amyloid Polypeptide (IAPP) Cao et al., 2021 Human, synthetic, amidated, wild type, seeded by Type 2 Diabetes Patient fibrils, Polymorph 1 7m61 CryoEM residues:13-37 resolution:3.8
72 △	Islet Amyloid Polypeptide (IAPP) Cao et al., 2021 Human, synthetic, amidated, wild type, seeded by Type 2 Diabetes Patient fibrils, Polymorph 2 7m62 CryoEM residues:6-37 resolution:3.9
73 △	Islet Amyloid Polypeptide (IAPP) Cao et al., 2021 Human, synthetic, amidated, wild type, seeded by Type 2 Diabetes Patient fibrils, Polymorph 3 7m64 CryoEM residues:13-37 resolution:4
74 △	Islet Amyloid Polypeptide (IAPP) Cao et al., 2021 Human, synthetic, amidated, wild type, seeded by Type 2 Diabetes Patient fibrils, Polymorph 4 7m65 CryoEM residues:6-37 resolution:4.1
75 △	Islet Amyloid Polypeptide (IAPP) Li et al., 2022 Human, synthetic, amidated C-term, wild type, no salt, slim form 7ykw CryoEM residues:11-37 resolution:3.6
76 △	Islet Amyloid Polypeptide (IAPP) Li et al., 2022 Human, synthetic, amidated C-term, wild type, no salt, thick form type 2 7yl0 CryoEM residues:1-37 resolution:3.2
77 △	Islet Amyloid Polypeptide (IAPP) Li et al., 2022 Human, synthetic, amidated C-term, wild type, no salt, thick form type 1 7yl3 CryoEM residues:1-37 resolution:3.2
78 △	Islet Amyloid Polypeptide (IAPP) Li et al., 2022 Human, synthetic, amidated C-term, wild type, no salt, thick form type 3 7yl7 CryoEM residues:1-37 resolution:3.3
79 △	Islet Amyloid Polypeptide (IAPP) S20G Gallardo et al., 2020 Human, synthetic, C-term amidated 6zrq cryoEM residues:15-37 resolution:3.9
80 △	Islet Amyloid Polypeptide (IAPP) S20G Gallardo et al., 2020 Human, synthetic, C-term amidated 6zrr cryoEM residues:15-37 resolution:4
	Protein Information	Polarity Map	Energy Map
81 △	α-synuclein Tuttle et al., 2016 Human, recombinant 2n0a ssNMR residues:43-97 resolution:0
82 △	α-synuclein Li et al., 2018 Human, recombinant 6a6b cryoEM residues:37-99 resolution:3.1
83 △	α-synuclein Li et al., 2018 Human, recombinant, rod polymorph 6cu7 cryoEM residues:38-97 resolution:3.5
84 △	α-synuclein Li et al., 2018 Human, recombinant 6cu8 cryoEM residues:43-83 resolution:3.6
85 △	α-synuclein Zhao et al., 2020b Human, semisynthetic, phospho-Y39, twist-dimer 6l1t cryoEM residues:1-100 resolution:3.22
86 △	α-synuclein Zhao et al., 2020b Human, semisynthetic, phospho-Y39, twist-trimer 6l1u cryoEM residues:1-100 resolution:3.37
87 △	α-synuclein Guerrero-Ferreira et al., 2019 Human, recombinant, fibril polymorph 2a 6rt0 cryoEM residues:14-25, 36-95 resolution:3.1
88 △	α-synuclein Guerrero-Ferreira et al., 2019 Human, recombinant, fibril polymorph 2b 6rtb cryoEM residues:9-24, 35-93 resolution:3.5
89 △	α-synuclein Guerrero-Ferreira et al., 2019 Human, recombinant, fibril polymorph 2b 6sst cryoEM residues:14-25, 36-96 resolution:3.4
90 △	α-synuclein Guerrero-Ferreira et al., 2019 Human, recombinant, fibril polymorph 2a 6ssx cryoEM residues:14-25, 36-96 resolution:3
91 △	α-synuclein Schweighauser et al., 2020 Human, extracted from Multiple System Atrophy patient brain Case 1, Type I fibril 6xyo cryoEM residues:14-99 resolution:2.6
92 △	α-synuclein Schweighauser et al., 2020 Human, extracted from Multiple System Atrophy patient brain, Case 2, Type II-1 fibril 6xyp cryoEM residues:14-99 resolution:3.3
93 △	α-synuclein Schweighauser et al., 2020 Human, extracted from Multiple Systems Atrophy patient brain, Case 2, Type II-2 fibril 6xyq cryoEM residues:14-99 resolution:3.1
94 △	α-synuclein Long et al., 2021 Human, recombinant, wild type seeded with E46K hereditary mutation 7c1d CryoEM residues:46-96 resolution:3.8
95 △	α-synuclein Hojjatian et al., 2021 Human, recombinant, formed in the presence of Tau 7l7h CryoEM residues:37-79 resolution:4
96 △	α-synuclein Lövestam et al., 2021 Human, recombinant, seeded from Multiple Systems Atrophy Case 2, Fold A, Doublet type 1 7nca CryoEM residues:37-97 resolution:3.47
97 △	α-synuclein Lövestam et al., 2021 Human, recombinant, seeded from Multiple Systems Atrophy Case 2, Fold A, Double type 2 7ncg CryoEM residues:37-97 resolution:3.43
98 △	α-synuclein Lövestam et al., 2021 Human, recombinant, seeded from Multiple Systems Atrophy Case 1, Fold B, Doublet type 1 7nch CryoEM residues:14-91 resolution:3.84
99 △	α-synuclein Lövestam et al., 2021 Human recombinant, seeded by Multiple Systems Atrophy Case 1, Fold B, Doublet type 2 7nci CryoEM residues:14-91 resolution:3.55
100 △	α-synuclein Lövestam et al., 2021 Human, recombinant, seeded by Multiple Systems Atrophy Case 1, Folds A and B, Doublet type 2 7ncj CryoEM residues:14-91 resolution:4.23
	Protein Information	Polarity Map	Energy Map
101 △	α-synuclein Lövestam et al., 2021 Human recombinant, seeded by Multiple Systems Atrophy Case 5, Type 3 Filaments 7nck CryoEM residues:36-99 resolution:3.18
102 △	α-synuclein Frieg et al., 2022 Human, recombinant, seeded from brain of Parkinson's Disease Patient 7ozg CryoEM residues:14-25,36-96 resolution:3.3
103 △	α-synuclein Frieg et al., 2022 Human, recombinant, seeded from Multiple Systems Atrophy 7ozh CryoEM residues:36-93 resolution:3.02
104 △	α-synuclein Tao et al., unpublished Human, recombinant, recombinant, heparin-induced, polymorph 1 7v4a CryoEM residues:14-25, 32-99 resolution:3.2
105 △	α-synuclein Tao et al., unpublished Human, recombinant, human, recombinant, heparin-induced, polymorph 3 7v4b CryoEM residues:14-25, 32-99 resolution:3.1
106 △	α-synuclein Tao et al., unpublished Human, recombinant, recombinant, heparin-induced, polymorph 4 7v4c CryoEM residues:37-98 resolution:3.3
107 △	α-synuclein Tao et al., unpublished Human, recombinant, heparin-remodeled 7v4d CryoEM residues:37-94 resolution:3.5
108 △	α-synuclein Tao et al., unpublished Human, recombinant, complex with ligand F0502B 7wmm CryoEM residues:37-97 resolution:2.6
109 △	α-synuclein Zhao et al., 2023 Human, recombinant, induced by ferric iron 7xjx CryoEM residues:37-99 resolution:2.7
110 △	α-synuclein Zhang et al., 2023 human, recombinant, non-acetylated, apo 7yk2 CryoEM residues:37-99 resolution:2.8
111 △	α-synuclein Zhang et al., 2023 human, recombinant, non-acetylated, with dLAG3 receptor 7yk8 CryoEM residues:14-25,37-99 resolution:2.8
112 △	α-synuclein Tao et al., 2023 unpublished Human, recombinant, Congo Red ligand (disordered) 7yng CryoEM residues:37-99 resolution:3.1
113 △	α-synuclein Tao et al., 2023 unpublished Human, recombinant, EB ligand 7ynl CryoEM residues:40-97 resolution:2.6
114 △	α-synuclein Tao et al., 2023 unpublished Human, recombinant, Thioflavin T ligand, conformation 1 7ynm CryoEM residues:37-97 resolution:2.9
115 △	α-synuclein Tao et al., 2023 unpublished Human, recombinant, Thioflavin T ligand, conformation 2 7ynn CryoEM residues:37-97 resolution:2.9
116 △	α-synuclein Tao et al., 2023 unpublished Human, recombinant, Pitssburgh compound B ligand, conformation 1 7yno CryoEM residues:37-97 resolution:2.8
117 △	α-synuclein Tao et al., 2023 unpublished Human, recombinant, BF227 ligand 7ynp CryoEM residues:37-97 resolution:2.8
118 △	α-synuclein Tao et al., 2023 unpublished Human, recombinant, Pittsburgh compound B ligand, conformation 2 7ynq CryoEM residues:37-97 resolution:2.8
119 △	α-synuclein Tao et al., 2023 unpublished Human, recombinant, C05-03 ligand (disordered) 7ynr CryoEM residues:37-97 resolution:2.9
120 △	α-synuclein Tao et al., 2023 unpublished Human, recombinant, SIL5 ligand (disordered) 7yns CryoEM residues:37-97 resolution:3
	Protein Information	Polarity Map	Energy Map
121 △	α-synuclein Tao et al., 2023 unpublished Human, recombinant, pFTAA ligand (disordered) 7ynt CryoEM residues:40-97 resolution:3.1
122 △	α-synuclein Frieg et al., 2022 Human, recombinant, heparin-remodeled 8a4l CryoEM residues:14-24, 33-96 resolution:3.22
123 △	α-synuclein Yang et al., 2022 Extracted from brain of a patient with Parkinson's Disease Dementia; fold is identical to Parkinson's Disease and Dementia with Lewy Bodies 8a9l CryoEM residues:14-22, 31-100 resolution:2.16
124 △	α-synuclein Frieg et al., 2022b human, recombinant, Lipidic, Polymorph L2B 8ads CryoEM residues:14-24,33-96 resolution:3.05
125 △	α-synuclein Frieg et al., 2022b human, recombinant, Lipidic, Polymorph L1A 8adu CryoEM residues:1-99 resolution:3.24
126 △	α-synuclein Frieg et al., 2022b human, recombinant, Lipidic, Polymorph L1B 8adv CryoEM residues:1-99 resolution:2.98
127 △	α-synuclein Frieg et al., 2022b human, recombinant, Lipidic, Polymorph L1C 8adw CryoEM residues:1-99 resolution:2.95
128 △	α-synuclein Frieg et al., 2022b human, recombinant, Lipidic, Polymorph L3A 8aex CryoEM residues:14-19,33-97 resolution:2.76
129 △	α-synuclein Sokratian et al., 2023 Human, recombinant, spontaneous control 8cyr CryoEM residues:15-24,36-97 resolution:4.2
130 △	α-synuclein Sokratian et al., 2023 Human, recombinant, seeded from Dementia with Lewy Bodies Case 1, Fibril Class 2b, extended pore, type 2 warp 8cys CryoEM residues:15-24,36-97 resolution:3.1
131 △	α-synuclein Sokratian et al., 2023 Human, recombinant, seeded from Dementia with Lewy Bodies Case 1, Fibril Class 2a, extended pore, type 1 warp 8cyt CryoEM residues:15-24,36-97 resolution:3
132 △	α-synuclein Sokratian et al., 2023 Human, recombinant, seeded from Dementia with Lewy Bodies Case 2, Fibril Class 2b, extended pore, type 1 & 2 warp 8cyv CryoEM residues:15-24,36-97 resolution:3.5
133 △	α-synuclein Sokratian et al., 2023 Human, recombinant, seeded from Dementia with Lewy Bodies Case 3, Fibril Class 2b, compact pore, type 1 warp 8cyw CryoEM residues:14-25,36-96 resolution:3.1
134 △	α-synuclein Sokratian et al., 2023 Human, recombinant, seeded from Dementia with Lewy Bodies Case 3, Fibril Class 2a, compact pore, type 1 warp 8cyx CryoEM residues:14-25,36-96 resolution:3
135 △	α-synuclein Sokratian et al., 2023 Human, recombinant, seeded from Dementia with Lewy Bodies Case 5, Fibril Class 2b, extended pore, type 1 & 2 warps 8cyy CryoEM residues:15-24,36-97 resolution:3.1
136 △	α-synuclein Sokratian et al., 2023 Human, recombinant, seeded from Dementia with Lewy Bodies Case 7, Fibril Class 2b, extended pore, type 1 warp 8cz0 CryoEM residues:15-24,36-97 resolution:2.9
137 △	α-synuclein Sokratian et al., 2023 Human, recombinant, seeded from Dementia with Lewy Bodies Case 7, Fibril Class 2b, extended pore, type 2 warp 8cz1 CryoEM residues:15-24,36-97 resolution:3
138 △	α-synuclein Sokratian et al., 2023 Human, recombinant, seeded from Dementia with Lewy Bodies Case 7, Fibril Class 2a, extended pore, type 1 warp 8cz2 CryoEM residues:15-24,36-97 resolution:3
139 △	α-synuclein Sokratian et al., 2023 Human, recombinant, seeded from Dementia with Lewy Bodies Case 10, Fibril Class 2b, extended pore, type 1 warp 8cz3 CryoEM residues:15-24,36-97 resolution:3.2
140 △	α-synuclein Sokratian et al., 2023 Human, recombinant, seeded from Dementia with Lewy Bodies Case 10, Fibril Class 2a, extended pore, type 1 warp 8cz6 CryoEM residues:15-24,36-97 resolution:3.2
	Protein Information	Polarity Map	Energy Map
141 △	α-synuclein Dhavale et al., 2023 Human, recombinant, seeded with fibrils from a patient with Dementia with Lewy bodies 8fpt CryoEM residues:30-103 resolution:100
142 △	α-synuclein (1-103), N-acetylated Ni et al., 2019 recombinant 6osm cryoEM residues:37-96 resolution:3.4
143 △	α-synuclein (1-121) Guerrero-Ferreira et al., 2018 Human, recombinant 6h6b cryoEM residues:38-95 resolution:3.4
144 △	α-synuclein (1-122), N-acetylated Ni et al., 2019 recombinant 6osl cryoEM residues:39-97 resolution:3
145 △	α-synuclein (1-140), N-acetylated Ni et al., 2019 Human, recombinant 6osj cryoEM residues:37-97 resolution:2.8
146 △	α-synuclein (41-140) McGlinchey et al., 2021 Human, recombinant 7lc9 CryoEM residues:46-96 resolution:3.2
147 △	α-synuclein A53E Sun et al., 2023 Human, recombinant, hereditary mutation 7uak CryoEM residues:38-99 resolution:3.38
148 △	α-synuclein A53T Sun et al., 2020 Human, recombinant, hereditary mutation 6lrq cryoEM residues:37-99 resolution:3.5
149 △	α-synuclein A53T Huang et al., unpublished Human, recombinant, hereditary mutation 7wnz CryoEM residues:37-100 resolution:3.4
150 △	α-synuclein A53T Huang et al., unpublished Human, recombinant, hereditary mutation 7wo0 CryoEM residues:35-99 resolution:2.7
151 △	α-synuclein E46K Zhao et al., 2020a Human, recombinant, hereditary mutation 6l4s cryoEM residues:45-99 resolution:3.37
152 △	α-synuclein E46K Boyer et al., 2020 Human, recombinant, hereditary mutation 6ufr cryoEM residues:36-98 resolution:2.5
153 △	α-synuclein G51D Sun et al., 2021 Human, recombinant, hereditary mutation 7e0f CryoEM residues:50-98 resolution:3.02
154 △	α-synuclein H50Q Boyer et al., 2019 Human, recombinant, hereditary mutation 6peo cryoEM residues:36-99 resolution:3.3
155 △	α-synuclein H50Q Boyer et al., 2019 Human, recombinant, hereditary mutation 6pes cryoEM residues:36-99 resolution:3.6
156 △	α-synuclein, human Fan et al., 2023 Recombinant, seeded from a Parkinson's Disease patient, preclinical, filament type 1A 7v47 CryoEM residues:36-96 resolution:2.8
157 △	α-synuclein, human Fan et al., 2023 Recombinant, seeded from a Parkinson's Disease patient, postmortem, filament type 1D 7v48 CryoEM residues:36-98 resolution:3
158 △	α-synuclein, human Fan et al., 2023 Recombinant, seeded from a Parkinson's Disease patient, postmortem, filament type 4 7v49 CryoEM residues:36-95 resolution:3.4
159 △	α-synuclein, human Fan et al., 2023 Recombinant, seeded from a Parkinson's Disease patient, mid-to-late stage 1, minor polymorph 7xo0 CryoEM residues:36-97 resolution:3
160 △	α-synuclein, human Fan et al., 2023 Recombinant, seeded from a Parkinson's Disease patient, mid-to-late stage 1, major polymorph 7xo1 CryoEM residues:37-97 resolution:3
	Protein Information	Polarity Map	Energy Map
161 △	α-synuclein, human Fan et al., 2023 Recombinant, seeded from a Parkinson's Disease patient, mid-to-late stage 4, minor polymorph 7xo2 CryoEM residues:36-97 resolution:3
162 △	α-synuclein, human Fan et al., 2023 Recombinant, seeded from a Parkinson's Disease patient, mid-to-late stage 4, filament type 1C 7xo3 CryoEM residues:36-98 resolution:2.6
163 △	α-synuclein, human Fan et al., 2023 Recombinant, seeded from a Parkinson's Disease patient, preclinical, major polymorph 8h03 CryoEM residues:36-96 resolution:2.8
164 △	α-synuclein, human Fan et al., 2023 Recombinant, seeded from a Parkinson's Disease patient, postmortem, major polymorph 8h04 CryoEM residues:36-98 resolution:3
165 △	α-synuclein, human Fan et al., 2023 Recombinant, seeded from a Parkinson's Disease patient, postmortem, minor polymorph 8h05 CryoEM residues:36-95 resolution:3.4
166 △	α-synuclein, human, mixture of wild type and MAAAEKT insertion after residue 22 Yang et al., 2023 Extracted from Juvenile-Onset Synucleinopathy patient brain, singlet filament 8bqv CryoEM residues:14-25,36-100 resolution:2
167 △	α-synuclein, human, mixture of wild type and MAAAEKT insertion after residue 22 Yang et al., 2023 Extracted from Juvenile-Onset Synucleinopathy patient brain, doublet filament 8bqw CryoEM residues:14-25,36-100 resolution:2.3
168 △	α-synuclein, human, mixture of wild type and MAAAEKT insertion after residue 22 Yang et al., 2023 Human, recombinant, type 1 filaments 8ce7 CryoEM residues:37-99 resolution:2.7
169 △	α-synuclein, human, mixture of wild type and MAAAEKT insertion after residue 22 Yang et al., 2023 Human, recombinant, type 2 filament 8ceb CryoEM residues:40-97 resolution:2.7
170 △	β-2-microglobulin Iwata et al., 2006 recombinant 2e8d ssNMR residues:20-41 resolution:0
171 △	β-2-microglobulin Iadanza et al., 2018 recombinant 6gk3 cryoEM residues:22-85 resolution:3.9
172 △	β-2-microglobulin Wilkinson et al., 2023 recombinant, fibril form 4PF 8a7q CryoEM residues:21-84 resolution:2.8
173 △	β-2-microglobulin D76N mutation Wilkinson et al., 2023 human, recombinant, fibril form 2PFa 8a7t CryoEM residues:6-90 resolution:3
174 △	β-2-microglobulin ΔN6 mutation Wilkinson et al., 2023 human, recombinant, fibril form 2PFa 8a7o CryoEM residues:6-93 resolution:3
175 △	β-2-microglobulin ΔN6 mutation Wilkinson et al., 2023 recombinant, fibril form 2PFb 8a7p CryoEM residues:6-92 resolution:3.4
176 △	β-endorphin Seuring et al., 2020 recombinant 6tub ssNMR residues:1-31 resolution:0
177 △	LECT2 Richards et al., 2023 Human, recombinant 8g2v CryoEM residues:55-74 resolution:2.72
178 △	Nup98 Ibáñez de Opakua, 2022 human, recombinant, polymorph 1 7q64 CryoEM residues:85-124 resolution:2.76
179 △	Nup98 Ibáñez de Opakua, 2022 human, recombinant, polymorph 2 7q65 CryoEM residues:85-124 resolution:3.32
180 △	Nup98 Ibáñez de Opakua, 2022 human, recombinant, polymorph 3 7q66 CryoEM residues:85-121 resolution:2.79
	Protein Information	Polarity Map	Energy Map
181 △	Nup98 Ibáñez de Opakua, 2022 human, recombinant, polymorph 4 7q67 CryoEM residues:87-119 resolution:3.37
182 △	Orb2 Hervás et al., 2020 extracted from Drosophila brain 6vps cryoEM residues:176-206 resolution:2.6
183 △	Prion Protein, hamster Chen et al., 2022 Recombinant, prepared in acidic solution 7yat CryoEM residues:119-143 resolution:2.2
184 △	Prion Protein, hamster Syrian Kraus et al., 2021 Extracted from clinically ill hamster brain, 263K prion strain, infectious 7lna CryoEM residues:95-227 resolution:3.14
185 △	Prion Protein, human Wang et al., 2020 Recombinant 6lni cryoEM residues:23-231 resolution:2.7
186 △	Prion Protein, human Hallinan et al., 2022 Extracted from patient with Gerstmann-Straussler-Scheinker disease, type I filament 7umq CryoEM residues:80-141 resolution:3.29
187 △	Prion Protein, human Hallinan et al., 2022 Extracted from patient with Gerstmann-Straussler-Scheinker disease, type IIb filament 7un5 CryoEM residues:80-141 resolution:3.13
188 △	Prion Protein, human, E196K mutation Wang et al., 2021 Recombinant 7dwv CryoEM residues:175-217 resolution:3.07
189 △	Prion Protein, human, M129 variant, (94-178) Glynn et al., 2020 Recombinant 6uur cryoEM residues:106-145 resolution:3.5
190 △	Prion Protein, human, Y145Stop Mutation Li et al., 2022 Recombinant 7rl4 CryoEM residues:108-141 resolution:2.86
191 △	Prion Protein, mouse Manka et al., 2022 Extracted from brains of a terminally ill mouse, anchorless, aRML prion strain, infectious 7qig CryoEM residues:94-225 resolution:2.7
192 △	Prion Protein, mouse Hoyt et al., 2022 Extracted from brains of terminally ill mice, anchorless, aRML prion strain, infectious 7td6 CryoEM residues:93-230 resolution:3
193 △	Prion Protein, mouse Manka et al., 2023 Extracted from brains of a terminally ill mouse, ME7 prion strain, infectious 8a00 CryoEM residues:94-229 resolution:2.6
194 △	Prion Protein, mouse Hoyt et al., 2022b Extracted from brains of terminally ill mice, a22L prion strain, infectious 8efu CryoEM residues:94-226 resolution:3.2
195 △	Prion Protein, mouse, PrP23-144 Li et al., 2022 Recombinant 8dja CryoEM residues:108-141 resolution:3.92
196 △	RIPK1 RIPK3, human Mompeán et al., 2018 recombinant 5v7z ssNMR residues:448-462, 532-549 resolution:0
197 △	RIPK1(516-539) Liu et al., 2023 unpublished mouse, recombinant 8ib0 ssNMR residues:516-539 resolution:99.01
198 △	RIPK3, human Wu et al., 2021 Recombinant 7da4 CryoEM residues:448-469 resolution:4.24
199 △	RIPK3, human Wu et al., 2021 Recombinant 7dac ssNMR residues:447-475 resolution:0.01
200 △	Serum Amyloid A, feline Schulte et al., 2022 Extracted from a short hair cat with AA amyloidosis, kidney 7zh7 CryoEM residues:19-94 resolution:3.3
	Protein Information	Polarity Map	Energy Map
201 △	Serum Amyloid A, human Liberta et al., 2019 Extracted from AA amyloidosis patient kidney, glomerular variant 6mst cryoEM residues:2-55 resolution:2.7
202 △	Serum Amyloid A, human Banerjee et al., 2022 Extracted from an AA amyloidosis patient kidney, vascular variant 7zky CryoEM residues:2-69 resolution:2.56
203 △	Serum Amyloid A, mouse Liberta et al., 2019 Extracted from spleen of a mouse with systemic AA amyloidosis, fibril morphology I 6dso cryoEM residues:1-69 resolution:3
204 △	Serum Amyloid A, mouse Bansal et al., 2021 Recombinant, fibril morphology i 6zcf cryoEM residues:1-37 resolution:2.73
205 △	Serum Amyloid A, mouse Bansal et al., 2021 Recombinant, fibril morphology ii 6zcg cryoEM residues:1-37 resolution:2.95
206 △	Serum Amyloid A, mouse Bansal et al., 2021 Extracted from spleen of a mouse with systemic AA amyloidosis, fibril morphology II 6zch cryoEM residues:1-69 resolution:3.5
207 △	Serum Amyloid A, mouse Heerde et al., 2022 Recombinant, seeded by ex vivo fibrils from mouse liver, fibril morphology I 7ovt CryoEM residues:1-69 resolution:2.69
208 △	SH3 Domain of PI3-kinase Röder et al., 2019 recombinant 6r4r cryoEM residues:1-77 resolution:3.4
209 △	Superoxide Dismutase Wang et al., 2022 Human, recombinant, full-length 7vzf CryoEM residues:3-55, 86-153 resolution:2.93
210 △	TAF15 Tetter et al., 2023 Human, extracted from FTLD-FET patient brain 8ons CryoEM residues:7-99 resolution:1.97
211 △	Tau (198-399) El Mammeri et al., 2023 Human, recombinant, observed at 24° C 8g54 ssNMR residues:274-325 resolution:0
212 △	Tau (198-399) El Mammeri et al., 2023 Human, recombinant, observed at 12° C 8g55 ssNMR residues:264-326 resolution:0
213 △	Tau (244-391) Lövestam et al., 2022 Human, recombinant, tetrasodium pyrophosphate, filament type 20a 7ql2 CryoEM residues:275-324 resolution:2.95
214 △	Tau (258-391) Lövestam et al., 2022 Human, recombinant, shaken at 700 rpm, filament type 38a 7qk3 CryoEM residues:270-330 resolution:2.44
215 △	Tau (258-391) Lövestam et al., 2022 Human, recombinant, heparan sulfate, 700 rpm, filament type 40a 7qk6 CryoEM residues:275-328 resolution:2.26
216 △	Tau (258-391) Lövestam et al., 2022 Human, recombinant, phosphoglycerate, 700 rpm, filament type 39a 7qkg CryoEM residues:275-328 resolution:3.36
217 △	Tau (258-391) Lövestam et al., 2022 Human, recombinant, sodium azide, filament type 41a 7qkh CryoEM residues:277-317 resolution:3.17
218 △	Tau (258-391) Lövestam et al., 2022 Human, recombinant, phosphoglycerate, shaken at 700rpm, filament type 39a 7qkk CryoEM residues:304-379 resolution:2.8
219 △	Tau (263-280) acetylated K274 and K280 Li et al., 2023 Human, synthetic 8fnz CryoEM residues:263-280 resolution:3.88
220 △	Tau (266-391) Lövestam et al., 2022 Human, recombinant, CTE-like fold, phosphate-buffered saline, filament type 23a 7ql1 CryoEM residues:306-378 resolution:3.34
	Protein Information	Polarity Map	Energy Map
221 △	Tau (266-391) and 3R/(297-391) Li et al., 2022 Human, Recombinant, PHF-like polymorph 7ymn CryoEM residues:304-379 resolution:3.46
222 △	Tau (266-391) S356D Lövestam et al., 2022 Human, recombinant, KCl, filament type 44a 7qkw CryoEM residues:275-328 resolution:2.32
223 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, LiCl, filament type 9a 7qjy CryoEM residues:305-379 resolution:3.14
224 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, LiCl, filament type 9b 7qjz CryoEM residues:305-378 resolution:3.4
225 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, KCl, filament type 10a 7qk5 CryoEM residues:306-379 resolution:1.92
226 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, Copper(II) chloride, filament type 12a 7qkf CryoEM residues:305-360 resolution:2.83
227 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, magnesium chloride, NaCl, filament type 14b 7qkj CryoEM residues:305-379 resolution:3.26
228 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, zinc chloride, filament type 11a 7qkl CryoEM residues:304-379 resolution:2.07
229 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, MgCl2 and NaCl, filament type 14a 7qku CryoEM residues:304-379 resolution:2.57
230 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, CTE-like fold, MgSO4, NaCl, filament type 15a 7qkv CryoEM residues:309-377 resolution:3.23
231 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, CTE-like fold, MgSO4, NaCl, filament type 15b 7qkx CryoEM residues:306-378 resolution:3.16
232 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, CTE-like fold, MgSO4, NaCl, filament type 15c 7ql0 CryoEM residues:306-378 resolution:3.13
233 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, NaCl, filament type 8b 7ql3 CryoEM residues:308-378 resolution:3.32
234 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, sodium bicarbonate, NaCl, filament type 16a 7r4t CryoEM residues:304-379 resolution:2.73
235 △	Tau (266-391)(297-391) Lövestam et al., 2022 Human, recombinant, KCl, filament type 10b 7r5h CryoEM residues:305-388 resolution:2.59
236 △	Tau (266-391), S356D Lövestam et al., 2022 Human, recombinant, NaCl, filament type 45a 7qkm CryoEM residues:274-328 resolution:2.66
237 △	Tau (297-391) Lövestam et al., 2022 Human, recombinant, AD-like fold, LiCl, filament type 2c 7qjv CryoEM residues:304-378 resolution:3.29
238 △	Tau (297-391) Lövestam et al., 2022 Human, recombinant, CTE type II-like polymorph, filament type 8a 7qjw CryoEM residues:305-379 resolution:2.81
239 △	Tau (297-391) Lövestam et al., 2022 Human, recombinant, shaken at 700 rpm, filament type 34b 7qjx CryoEM residues:304-378 resolution:2.99
240 △	Tau (297-391) Lövestam et al., 2022 Human, recombinant, PHF-like polymorph, 200 mM MgCl2, 200 rpm, filament type 4a 7ql4 CryoEM residues:304-379 resolution:3.2
	Protein Information	Polarity Map	Energy Map
241 △	Tau (297-391) Li et al., 2022 Human, Recombinant, spindle-like fold 7ypg CryoEM residues:304-362 resolution:2.54
242 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, First Intermediate Amyloid (FIA) on pathway to AD and CTE folds 8ppo CryoEM residues:302-316 resolution:2
243 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA1 8q27 CryoEM residues:303-379 resolution:2.02
244 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA2 8q2j CryoEM residues:303-380 resolution:3.23
245 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA3 8q2k CryoEM residues:305-379 resolution:2.88
246 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA5 8q7f CryoEM residues:304-378 resolution:3.72
247 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA6 8q7l CryoEM residues:306-379 resolution:2.82
248 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA7 8q7m CryoEM residues:304-379 resolution:3.26
249 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA8 8q7p CryoEM residues:304-378 resolution:3.28
250 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA11 8q7t CryoEM residues:304-378 resolution:3
251 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Late Intermediate Amyloid on Pathway to AD fold, AD-LIA2 8q88 CryoEM residues:304-379 resolution:2.95
252 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA10 8q8c CryoEM residues:304-378 resolution:1.92
253 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Late Intermediate Amyloid on Pathway to AD fold, AD-LIA6 8q8d CryoEM residues:304-379 resolution:3.04
254 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Late Intermediate Amyloid on Pathway to CTE fold, CTE-LIA3 8q9f CryoEM residues:305-379 resolution:1.91
255 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Late Intermediate Amyloid on Pathway to CTE fold, CTE-LIA5 8q9g CryoEM residues:306-378 resolution:2.65
256 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Late Intermediate Amyloid on Pathway to CTE fold, CTE-LIA6 8q9i CryoEM residues:306-378 resolution:2.56
257 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Late Intermediate Amyloid on Pathway to CTE fold, CTE-LIA7 8q9j CryoEM residues:306-378 resolution:2.96
258 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Late Intermediate Amyloid on Pathway to CTE fold, CTE-LIA13 8q9k CryoEM residues:306-379 resolution:3.2
259 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Late Intermediate Amyloid on Pathway to CTE fold, CTE-LIA14 8q9l CryoEM residues:306-378 resolution:2.76
260 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, CTE fold type I (CTE-I) 8q9m CryoEM residues:305-379 resolution:2.65
	Protein Information	Polarity Map	Energy Map
261 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, CTE fold type II (CTE-II-like) 8q9o CryoEM residues:305-379 resolution:3.1
262 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Late Intermediate Amyloid on Pathway to AD fold, AD-LIA8 8qcp CryoEM residues:304-379 resolution:3.21
263 △	Tau (297-391) Lövestam et al., 2023 Human, recombinant, Middle Intermediate Amyloid on Pathway to CTE fold, CTE-MIA12 8qcr CryoEM residues:305-379 resolution:2.75
264 △	Tau (297-394) Lövestam et al., 2022 Human, recombinant, phosphate buffered saline, filament type 35d 7qk1 CryoEM residues:305-379 resolution:3.03
265 △	Tau (297-408) S396D, S400D, T403D Lövestam et al., 2022 Human, recombinant, AD-like fold, filament type 42a 7qki CryoEM residues:304-379 resolution:3.13
266 △	Tau (300-391) Lövestam et al., 2022 Human, recombinant, phosphate buffered saline, filament type 36a 7qk2 CryoEM residues:308-378 resolution:2.61
267 △	Tau (305-379) Lövestam et al., 2022 human, recombinant, filament type 27a 7qkz CryoEM residues:307-317 resolution:2.65
268 △	Tau 0N4R with phosphoserine Lövestam et al., 2022 Human, recombinant, filament type 47a 7qky CryoEM residues:376-441 resolution:1.83
269 △	Tau 2N4R and RNA Abskharon et al., 2022 Human, recombinant, grown in presence of RNA 7sp1 CryoEM residues:391-426 resolution:3.4
270 △	Tau 3R Falcon et al., 2018 Human, extracted from brain of a Pick's Disease patient, Pick fold 6gx5 cryoEM residues:254-274, 306-378 resolution:3.2
271 △	Tau 3R Zhang et al., 2019 human, recombinant, heparin Induced 6qjq cryoEM residues:272-330 Δ275-305 resolution:3.5
272 △	Tau 3R Tarutani et al., 2023 Extracted from human SH-SY5Y cell culture, seeded with brain of a patient with Alzheimers Disease 8ore CryoEM residues:273-274,306-380 resolution:2.5
273 △	Tau 3R Schweighauser et al., 2023 Human, extracted from brain of a patient with Pick's Disease and MAPT ΔK281 mutation 8p34 CryoEM residues:254-274, 306-378 resolution:2.61
274 △	Tau 3R and 4R Fitzpatrick et al., 2017 Human, extracted from Alzheimer patient brain, Paired Helical Filament 5o3l cryoEM residues:306-378 resolution:3.4
275 △	Tau 3R and 4R Fitzpatrick et al., 2017 Human, extracted from Alzheimers patient brain, Straight Filament 5o3t cryoEM residues:306-378 resolution:3.4
276 △	Tau 3R and 4R Hallinan et al., 2021 Human, extracted from PrP Cerebral Amyloid Angiopathy Patient Brain, Paired Helical Filament 7mkf CryoEM residues:306-378 resolution:3
277 △	Tau 3R and 4R Hallinan et al., 2021 Human, extracted from PrP Cerebral Amyloid Angiopathy Patient Brain, Straight Filament 7mkg CryoEM residues:306-378 resolution:3.07
278 △	Tau 3R and 4R Hallinan et al., 2021 Human, extracted from Gerstmann-Sträussler-Scheinker Patient Brain, Paired Helical Filament 7mkh CryoEM residues:305-379 resolution:3.3
279 △	Tau 3R and 4R Shi et al., 2021 Human, extracted from Primary Age-Related Tauopathy Patient Brain, Case 3, Paired Helical Filament 7nrq CryoEM residues:304-380 resolution:2.76
280 △	Tau 3R and 4R Shi et al., 2021 Human, extracted from Primary Age-Related Tauopathy Patient Brain, Case 3, Straight Filament Conformation 1 7nrs CryoEM residues:304-380 resolution:2.68
	Protein Information	Polarity Map	Energy Map
281 △	Tau 3R and 4R Shi et al., 2021 Human, extracted from Primary Age-Related Tauopathy Patient Brain, Case 3, Straight Filament Conformation 2 7nrt CryoEM residues:304-380 resolution:2.68
282 △	Tau 3R and 4R Shi et al., 2021 Human, extracted from Alzheimers Patient Brain and Stained with PET ligand APN1607, Paired Helical Filament 7nrv CryoEM residues:304-380 resolution:3
283 △	Tau 3R and 4R Shi et al., 2021 Human, extracted from Alzheimers Patient Brain and Stained with PET ligand APN1607, Straight Filament 7nrx CryoEM residues:304-380 resolution:3.55
284 △	Tau 3R and 4R Seidler et al., 2022 Human, extracted from Alzheimers Patient Brain and soaked with EGCG for 0 hours 7upe CryoEM residues:304-379 resolution:3.4
285 △	Tau 3R and 4R Seidler et al., 2022 Human, extracted from Alzheimers Patient Brain and soaked with EGCG for 1 hour 7upf CryoEM residues:306-379 resolution:3.3
286 △	Tau 3R and 4R Seidler et al., 2022 Human, extracted from Alzheimers Patient Brain and soaked with EGCG for 3 hours 7upg CryoEM residues:306-379 resolution:3.8
287 △	Tau 3R and 4R Stern et al., 2023 Human, extracted from Alzheimers patient brain, Paired Helical Filament, aqueous fraction 8azu CryoEM residues:306-379 resolution:3.1
288 △	Tau 3R and 4R Fowler et al., 2023 Human, extracted from Alzheimers patient brain, Paired Helical Filament, extracellular vesicle fraction 8bgs CryoEM residues:305-379 resolution:3.16
289 △	Tau 3R and 4R Fowler et al., 2023 Human, extracted from Alzheimers patient brain, Paired Helical Filament, cellular fraction 8bgv CryoEM residues:305-379 resolution:3.27
290 △	Tau 3R and 4R Merz et al., 2023 Human, extracted from Alzheimers Patient Brain and Stained with PET ligand GTP-1, Paired Helical Filament 8fug CryoEM residues:306-378 resolution:2.7
291 △	Tau 4R Falcon et al., 2019 Human, extracted from Chronic Traumatic Encephalopathy patient brain, filament CTE Type 1 6nwp cryoEM residues:305-379 resolution:2.3
292 △	Tau 4R Falcon et al., 2019 Human, extracted from Chronic Traumatic Encephalopathy patient brain, filament CTE Type 2 6nwq cryoEM residues:305-379 resolution:3.4
293 △	Tau 4R Zhang et al., 2019 Human, recombinant, heparin induced, Snake Polymorph 6qjh cryoEM residues:272-330 resolution:3.3
294 △	Tau 4R Zhang et al., 2019 Human, recombinant, heparin induced, Twister Polymorph 6qjm cryoEM residues:274-292, 304-321 resolution:3.3
295 △	Tau 4R Zhang et al., 2019 Human, recombinant, heparin induced, Jagged Polymorph 6qjp cryoEM residues:274-290, 304-321 resolution:3.5
296 △	Tau 4R Zhang et al., 2020 Human, extracted from brain of Corticobasal Degeneration patient, filament CBD Type 1 6tjo cryoEM residues:274-380 resolution:3.2
297 △	Tau 4R Zhang et al., 2020 Human, extracted from brain of Corticobasal Degeneration patient, filament CBD Type 2 6tjx cryoEM residues:274-380 resolution:3
298 △	Tau 4R Shi et al., 2021 Human, extracted from Progressive Supranuclear Palsy Patient Brain, PSP Filament 7p65 CryoEM residues:272-381 resolution:2.7
299 △	Tau 4R Shi et al., 2021 Extracted from Globular Glial Tauopathy Patient Brain, Filament GGT Type 1 7p66 CryoEM residues:272-379 resolution:3
300 △	Tau 4R Shi et al., 2021 Extracted from Globular Glial Tauopathy Patient Brain, Filament GGT Type 2 7p67 CryoEM residues:272-379 resolution:3.1
	Protein Information	Polarity Map	Energy Map
301 △	Tau 4R Shi et al., 2021 Human, extracted from Globular Glial Tauopathy (GGT) Patient Brain, Filament Type 3 7p68 CryoEM residues:272-379 resolution:2.87
302 △	Tau 4R Shi et al., 2021 Human, extracted from Globular Glial Tauopathy Patient Brain, Filament GGT Type 3 7p6a CryoEM residues:272-379 resolution:1.9
303 △	Tau 4R Shi et al., 2021 Human, extracted from Limbic-Predominant Neuronal Inclusion Body 4R Tauopathy Patient Brain, Filament LNT Type 1b 7p6b CryoEM residues:272-379 resolution:2.5
304 △	Tau 4R Shi et al., 2021 Human, extracted from Limbic-Predominant Neuronal Inclusion Body 4R Tauopathy Patient Brain, Filament LNT Type 2 7p6c CryoEM residues:272-379 resolution:2.2
305 △	Tau 4R Shi et al., 2021 Human, extracted from Argyrophilic Grain Disease Patient Brain, AGD Filament Type 1 7p6d CryoEM residues:273-387 resolution:3.3
306 △	Tau 4R Shi et al., 2021 Human, extracted from Argyrophilic Grain Disease Patient Brain, AGD Filament Type 2 7p6e CryoEM residues:274-381 resolution:3.4
307 △	Tau 4R Chang et al., 2022 Human, extracted from Progressive Supranuclear Palsy (PSP) Patient Brain, Case 1 7u0z CryoEM residues:272-381 resolution:4.2
308 △	Tau 4R Shi et al., 2022 Human, extracted from Chronic Traumatic Encephalopathy patient brain, filament CTE Type 1, complex with PET ligand flortaucipir 8byn CryoEM residues:305-379 resolution:2.6
309 △	Tau 4R Tarutani et al., 2023 Extracted from human SH-SY5Y cell culture, seeded with brain of a patient with Corticobasal Degeneration, Filament Type I 8orf CryoEM residues:277-377 resolution:2.5
310 △	Tau 4R Tarutani et al., 2023 Extracted from human SH-SY5Y cell culture, seeded with brain of a patient with Corticobasal Degeneration, Filament Type II 8org CryoEM residues:277-362 resolution:2.3
311 △	TDP-43 Arseni et al., 2021 Human, extracted from patient with Amyotrophic Lateral Sclerosis and Fronto-Temporal Lobar Degeneration type B 7py2 CryoEM residues:282-360 resolution:2.59
312 △	TDP-43 Arseni et al., 2023 Human, extracted from patient with Fronto-temporal Lobar Degeneration type A, filament block variant 1 8cg3 CryoEM residues:272-360 resolution:2.39
313 △	TDP-43 Arseni et al., 2023 Human, extracted from Patient with Fronto-temporal Lobar Degeneration type A, filament block variant 2 8cgg CryoEM residues:281-360 resolution:2.5
314 △	TDP-43 Arseni et al., 2023 Human, extracted from patient with Fronto-temporal Lobar Degeneration type A, filament block variant 3 8cgh CryoEM residues:281-360 resolution:2.68
315 △	TDP-43 Sharma et al., 2024 Human, recombinant, full-length, morphology 1a 8qx9 CryoEM residues:304-348 resolution:3.76
316 △	TDP-43 Sharma et al., 2024 Human, recombinant, full-length, morphology 1b 8qxa CryoEM residues:304-348 resolution:4.05
317 △	TDP-43 Sharma et al., 2024 Human, recombinant, full-length, morphology 2 8qxb CryoEM residues:304-348 resolution:3.86
318 △	TDP-43 (247-257) Guenther et al., 2018 synthetic 5w7v cryoEM residues:247-257 resolution:3.7
319 △	TDP-43 (279-360) Kumar et al., 2023 Human, recombinant, singlet fibril 7q3u CryoEM residues:281-351 resolution:3.7
320 △	TDP-43 (311-360) Cao et al., 2019 recombinant 6n37 cryoEM residues:312-347 resolution:3.8
	Protein Information	Polarity Map	Energy Map
321 △	TDP-43 (311-360) Cao et al., 2019 recombinant 6n3a cryoEM residues:311-360 resolution:3.3
322 △	TDP-43 (311-360) Cao et al., 2019 recombinant 6n3b cryoEM residues:312-352 resolution:3.8
323 △	TDP-43 A315E (286-331) Cao et al., 2019 recombinant 6n3c cryoEM residues:288-319 resolution:3.3
324 △	TDP-43 Low Complexity Domain (267-414) Li et al., 2021 recombinant 7kwz cryoEM residues:276-414 resolution:3.2
325 △	TFG(237-327) G269V Rosenberg et al., 2023 Human, recombinant, G269V mutation, low complexity domain (237-327) 8teq CryoEM residues:262-290 resolution:2.84
326 △	TFG(237-327) P285L Rosenberg et al., 2023 Human, recombinant, P285L mutation, low complexity domain (237-327) 8ter CryoEM residues:265-299 resolution:2.59
327 △	TMEM106B Schweighauser et al., 2022 Human, extracted from Patient with Alzheimer's Disease, case 1 7qvc CryoEM residues:120-254 resolution:2.64
328 △	TMEM106B Schweighauser et al., 2022 Extracted from Patient with Multiple Systems Atrophy, case 18, fibril fold I-d 7qvf CryoEM residues:120-254 resolution:3.64
329 △	TMEM106B Schweighauser et al., 2022 Human, extracted from Patient with Multiple Systems Atrophy, case 19, filament fold II-a 7qwg CryoEM residues:120-254 resolution:3.38
330 △	TMEM106B Schweighauser et al., 2022 Human, extracted from Patient with Multiple Systems Atrophy, case 19, filament fold II-b 7qwl CryoEM residues:120-254 resolution:3.47
331 △	TMEM106B Schweighauser et al., 2022 Human, extracted from Patient with Multiple Systems Atrophy, case 17, filament fold III 7qwm CryoEM residues:120-254 resolution:2.76
332 △	TMEM106B Jiang et al., 2022 Human, extracted from Patient with Fronto-temporal Lobar Degeneration, Type C, fibril polymorph 1 7saq CryoEM residues:120-254 resolution:2.9
333 △	TMEM106B Jiang et al., 2022 Human, extracted from patient with Fronto-temporal Lobar Degeneration, Type C, fibril polymorph 2 7sar CryoEM residues:120-254 resolution:3.2
334 △	TMEM106B Jiang et al., 2022 Human, extracted from brain of a patient with Fronto-temporal Lobar Degeneration Type C, Fibril polymorph 3 7sas CryoEM residues:120-254 resolution:3.7
335 △	TMEM106B Chang et al., 2022 Human, extracted from Patient with Progressive Supranuclear Palsy, case 2, singlet filament 7u10 CryoEM residues:120-254 resolution:3
336 △	TMEM106B Chang et al., 2022 Human, extracted from patient with Fronto-temporal Lobar Degeneration, Type A, case 1, singlet filament 7u11 CryoEM residues:120-254 resolution:3.2
337 △	TMEM106B Chang et al., 2022 Human, extracted from patient with Fronto-temporal Lobar Degeneration, Type A, case 2, singlet filament 7u12 CryoEM residues:120-254 resolution:3.5
338 △	TMEM106B Chang et al., 2022 Human, extracted from patient with Fronto-temporal Lobar Degeneration, Type A, case 4, singlet filament 7u13 CryoEM residues:120-254 resolution:2.9
339 △	TMEM106B Chang et al., 2022 Human, extracted from patient with Fronto-temporal Lobar Degeneration, Type C, case 8, singlet filament 7u14 CryoEM residues:120-254 resolution:4.5
340 △	TMEM106B Chang et al., 2022 Human, extracted from Patient with Fronto-temporal Lobar Degeneration, Type B, case 7, singlet filament 7u15 CryoEM residues:120-254 resolution:3
	Protein Information	Polarity Map	Energy Map
341 △	TMEM106B Chang et al., 2022 Human, extracted from Patient with Fronto-temporal Lobar Degeneration, Type A, all cases combined, singlet filament 7u16 CryoEM residues:120-254 resolution:2.7
342 △	TMEM106B Chang et al., 2022 Human, extracted from Patient with Fronto-temporal Lobar Degeneration, Type B, all cases combined, singlet filament 7u17 CryoEM residues:120-254 resolution:3
343 △	TMEM106B Chang et al., 2022 Human, extracted from Patient with Fronto-temporal Lobar Degeneration, Type A, all cases combined 7u18 CryoEM residues:120-254 resolution:2.7
344 △	TMEM106B Fan et al., 2022 Human, extracted from brain of 101 year old human with no diagnosed disease 7x83 CryoEM residues:120-254 resolution:3.4
345 △	TMEM106B Fan et al., 2022 Human, extracted from brain of patient with Parkinsons Disease Dementia 7x84 CryoEM residues:120-254 resolution:3
346 △	Transforming Growth Factor Beta Induced Protein, TGFBIp(611-633), G623R Low et al., 2023 Human, recombinant 8hia CryoEM residues:611-633 resolution:4.9
347 △	Transthyretin Steinebrei et al., 2022 Human, wild type, extracted from the heart a Senile Systemic Amyloidosis Patient 7z40 CryoEM residues:11-35, 57-123 resolution:2.78
348 △	Transthyretin Steinebrei et al., 2022 Human, wild type, extracted from the heart a Senile Systemic Amyloidosis Patient 8ade CryoEM residues:11-35, 57-123 resolution:2.78
349 △	Transthyretin Nguyen et al., 2023 Human, wild type, extracted from the heart a Transthyretin Amyloidosis Patient 8e7d CryoEM residues:11-34, 58-123 resolution:3.31
350 △	Transthyretin Nguyen et al., 2023 Human, wild type, extracted from the heart a Transthyretin Amyloidosis Patient 8e7h CryoEM residues:12-35, 58-123 resolution:3.7
351 △	Transthyretin, I84S Nguyen et al., 2023 Human, I84S mutation, extracted from the heart a Transthyretin Amyloidosis Patient 8e7e CryoEM residues:14-32, 67-122 resolution:3.61
352 △	Transthyretin, I84S Nguyen et al., 2023 Human, I84S mutation, extracted from the heart a Transthyretin Amyloidosis Patient 8e7j CryoEM residues:12-35, 64-122 resolution:3.1
353 △	Transthyretin, P24S Nguyen et al., 2023 Human, P24S mutation, extracted from the heart a Transthyretin Amyloidosis Patient 8e7i CryoEM residues:12-34, 58-123 resolution:3.65
354 △	Transthyretin, V30M Schmidt et al., 2019 Human, V30M mutation, extracted from heart of a patient with hereditary V30M ATTR Amyloidosis 6sdz cryoEM residues:11-35, 57-123 resolution:3
355 △	Transthyretin, V30M Iakovleva et al., 2021 Human, V30M mutation, extracted from the eye of an Amyloid Transthyretin Amyloidosis (ATTR) Patient 7ob4 CryoEM residues:11-35, 57-123 resolution:3.22