| Protein Information | Polarity Map | Energy Map |
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1 △ | |  |  |
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2 △ | |  |  |
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3 △ | |  |  |
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4 △ | |  |  |
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5 △ | Amyloid-β(1-40) |
Lu et al., 2013 |
Human, recombinant, seeded from Alzheimers Disease patient brain |
2m4j | ssNMR |
residues:1-40 | resolution:0 |
|  |  |
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|
6 △ | Amyloid-β(1-40) |
Kollmer et al., 2019 |
Human, extracted from Alzheimers Disease patient brain, meningeal tissue |
6shs | cryoEM |
residues:1-40 | resolution:4.4 |
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7 △ | |  |  |
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|
8 △ | Amyloid-β(1-40) |
Ghosh et al., 2021 |
Human, recombinant, seeded with fibrils extracted Alzheimers Disease patient brain, cortical tissue |
6w0o | cryoEM |
residues:10-40 | resolution:2.77 |
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9 △ | |  |  |
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10 △ | Amyloid-β(1-40) D23N, Iowa Mutation |
Qiang et al., 2012 |
Human, recombinant |
2lnq | ssNMR |
residues:15-40 | resolution:0 |
|  |  |
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11 △ | |  |  |
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12 △ | Amyloid-β(1-40) E22G, Arctic mutation |
Yang et al., 2023 |
Human, extracted from Alzheimer's patient brain |
8bg0 | CryoEM |
residues:11-40 | resolution:1.99 |
|  |  |
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|
13 △ | Amyloid-β(1-40) E22G, Arctic mutation |
Yang et al., 2023 |
Human, extracted from Alzheimer's mouse model brain |
8bg9 | CryoEM |
residues:1-37 | resolution:3.5 |
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14 △ | |  |  |
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15 △ | |  |  |
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16 △ | |  |  |
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17 △ | |  |  |
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18 △ | |  |  |
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19 △ | |  |  |
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20 △ | |  |  |
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| Protein Information | Polarity Map | Energy Map |
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21 △ | Amyloid-β(1-42) |
Liu et al., 2021 |
Human, synthetic, glycosylated at Tyr10 |
7f29 | CryoEM |
residues:6-42 | resolution:3.1 |
|  |  |
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22 △ | Amyloid-β(1-42) |
Yang et al., 2021 |
Human, extracted from Alzheimers Disease patient brain, Type 1 fibrils |
7q4b | CryoEM |
residues:9-42 | resolution:2.5 |
|  |  |
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|
23 △ | Amyloid-β(1-42) |
Yang et al., 2021 |
Human, extracted from Alzheimers Disease patient brain, Type 2 fibrils |
7q4m | CryoEM |
residues:12-42 | resolution:2.8 |
|  |  |
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|
24 △ | Amyloid-β(1-42) |
Stern et al., 2023 |
Human, aqueous extract from Alzheimers Disease patient brain, Type 1 fibrils |
8azs | CryoEM |
residues:9-42 | resolution:2.9 |
|  |  |
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25 △ | Amyloid-β(1-42) |
Stern et al., 2023 |
Human, aqueous extracts from the brain of a patient with Alzheimers Disease, type II filaments |
8azt | CryoEM |
residues:12-42 | resolution:3.7 |
|  |  |
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|
26 △ | Amyloid-β(1-42) |
Lee et al., 2023 |
Human, recombinant, seeded from the brain of a human with Alzheimers Disease, type A fibril |
8ezd | CryoEM |
residues:12-42 | resolution:2.83 |
|  |  |
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|
27 △ | Amyloid-β(1-42) |
Lee et al., 2023 |
Human, recombinant, seeded from the brain of a human with Alzheimers Disease |
8eze | CryoEM |
residues:1-42 | resolution:2.76 |
|  |  |
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|
28 △ | Amyloid-β(1-42) E22G, Arctic mutation |
Leistner et al., 2023 |
Human, extracted from AppNL-G-F familial AD mouse model brain |
8bfa | CryoEM |
residues:1-38 | resolution:3 |
|  |  |
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29 △ | Amyloid-β(1-42) E22G, Arctic mutation |
Leistner et al., 2023 |
Human, extracted from AppNL-G-F familial AD mouse model brain, and stained with methoxy-X04 |
8bfb | CryoEM |
residues:1-38 | resolution:3.2 |
|  |  |
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30 △ | Amyloid-β(1-42) E22G, Arctic mutation |
Yang et al., 2023 |
Human, extracted from Alzheimers Patient Brain |
8bfz | CryoEM |
residues:12-42 | resolution:2.8 |
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31 △ | |  |  |
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32 △ | |  |  |
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33 △ | Antibody Light Chain λ1 |
Radamaker et al., 2019 |
Human, extracted from cardiac AL amyloidosis patient heart |
6ic3 | cryoEM |
residues:15-105 | resolution:4 |
|  |  |
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|
34 △ | Antibody Light Chain λ1 |
Radamaker et al., 2021 |
Extracted from heart of a patient with systemic AL amyloidosis |
7nsl | CryoEM |
residues:9-52, 68-108 | resolution:3.1 |
|  |  |
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|
35 △ | Antibody Light Chain λ3 |
Radamaker et al., 2021 |
Human, extracted from cardiac AL amyloidosis patient heart, fibril conformation B |
6z1i | cryoEM |
residues:9-49, 68-107 | resolution:3.4 |
|  |  |
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36 △ | Antibody Light Chain λ3 |
Radamaker et al., 2021 |
Human, extracted from cardiac AL amyloidosis patient heart, fibril conformation A |
6z1o | cryoEM |
residues:9-49, 60-107 | resolution:3.2 |
|  |  |
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|
37 △ | Antibody Light Chain λ6 |
Swuec et al., 2019 |
Human, extracted from amyloid cardiomyopathy patient heart |
6hud | cryoEM |
residues:1-37, 66-105 | resolution:3.3 |
|  |  |
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|
38 △ | Antibody Light Chain λ6 |
Puri et al., 2023 |
Human, extracted from AL amyloidosis patient kidney |
8cpe | CryoEM |
residues:1-37, 66-105 | resolution:4 |
|  |  |
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|
39 △ | Antimicrobial peptide aurein 3.3 |
Bücker et al., 2022 |
Blue-thighed tree frog, synthetic |
7qv6 | CryoEM |
residues:1-17 | resolution:3.5 |
|  |  |
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|
40 △ | Antimicrobial peptide uperin 3.5 |
Bücker et al., 2022 |
Mjobergs toadlet, synthetic |
7qv5 | CryoEM |
residues:1-17 | resolution:3 |
|  |  |
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|
| Protein Information | Polarity Map | Energy Map |
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41 △ | |  |  |
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|
42 △ | De novo, Biphenyl-4-peptidyl-ffsy D-peptide |
Guo et al., 2023 |
Synthetic, induces cells to form spheroids |
8fof | CryoEM |
residues:1-5 | resolution:2.6 |
|  |  |
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|
43 △ | De novo, Catalytic Amyloid Fibril, Ac-LHLHLRL-NH2, p-nitrophenyl hydrolase |
Heerde et al., 2023 |
Synthetic |
8b3a | CryoEM |
residues:1-7 | resolution:3.8 |
|  |  |
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|
44 △ | De novo, Nitrobenzoxadiazole-ffsy D-peptide |
Guo et al., 2023 |
Synthetic, class 1 fibril, induces cells to form spheroids |
7t6e | CryoEM |
residues:1-5 | resolution:3.1 |
|  |  |
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|
45 △ | De novo, Nitrobenzoxadiazole-ffsy D-peptide |
Guo et al., 2023 |
Synthetic, class 2 fibril, induces cells to form spheroids |
8dst | CryoEM |
residues:1-5 | resolution:3.2 |
|  |  |
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46 △ | De novo, Pyrene IDP |
Wang et al., 2023 |
synthetic, intrinsically disordered short peptide forms fibrils |
7uuq | CryoEM |
residues:1-6 | resolution:3.1 |
|  |  |
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47 △ | De novo, Virus Enhancing Amyloid Fibril, PNF-18, CKFKFQF |
Heerde et al., 2023 |
Synthetic |
8okr | CryoEM |
residues:1-7 | resolution:2.86 |
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48 △ | |  |  |
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49 △ | |  |  |
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50 △ | |  |  |
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51 △ | |  |  |
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52 △ | |  |  |
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53 △ | |  |  |
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54 △ | |  |  |
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55 △ | |  |  |
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56 △ | |  |  |
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57 △ | |  |  |
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58 △ | |  |  |
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59 △ | |  |  |
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60 △ | |  |  |
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| Protein Information | Polarity Map | Energy Map |
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61 △ | |  |  |
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62 △ | Islet Amyloid Polypeptide (IAPP) |
Cao et al., 2020 |
Human, recombinant, SUMO-tagged |
6vw2 | cryoEM |
residues:14-37 | resolution:3.7 |
|  |  |
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|
63 △ | Islet Amyloid Polypeptide (IAPP) |
Röder et al., 2020 |
Human, synthetic, C-term amidated |
6y1a | cryoEM |
residues:13-37 | resolution:4.2 |
|  |  |
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|
64 △ | Islet Amyloid Polypeptide (IAPP) |
Gallardo et al., 2020 |
Human, synthetic, C-term amidated |
6zrf | cryoEM |
residues:13-37 | resolution:3.6 |
|  |  |
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|
65 △ | Islet Amyloid Polypeptide (IAPP) |
Cao et al., 2021 |
Human, synthetic, amidated, wild type, seeded by Type 2 Diabetes Patient fibrils, Polymorph 1 |
7m61 | CryoEM |
residues:13-37 | resolution:3.8 |
|  |  |
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|
66 △ | Islet Amyloid Polypeptide (IAPP) |
Cao et al., 2021 |
Human, synthetic, amidated, wild type, seeded by Type 2 Diabetes Patient fibrils, Polymorph 2 |
7m62 | CryoEM |
residues:6-37 | resolution:3.9 |
|  |  |
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|
67 △ | Islet Amyloid Polypeptide (IAPP) |
Cao et al., 2021 |
Human, synthetic, amidated, wild type, seeded by Type 2 Diabetes Patient fibrils, Polymorph 3 |
7m64 | CryoEM |
residues:13-37 | resolution:4 |
|  |  |
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|
68 △ | Islet Amyloid Polypeptide (IAPP) |
Cao et al., 2021 |
Human, synthetic, amidated, wild type, seeded by Type 2 Diabetes Patient fibrils, Polymorph 4 |
7m65 | CryoEM |
residues:6-37 | resolution:4.1 |
|  |  |
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|
69 △ | Islet Amyloid Polypeptide (IAPP) |
Li et al., 2022 |
Human, synthetic, amidated C-term, wild type, no salt, slim form |
7ykw | CryoEM |
residues:11-37 | resolution:3.6 |
|  |  |
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|
70 △ | Islet Amyloid Polypeptide (IAPP) |
Li et al., 2022 |
Human, synthetic, amidated C-term, wild type, no salt, thick form type 2 |
7yl0 | CryoEM |
residues:1-37 | resolution:3.2 |
|  |  |
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|
71 △ | Islet Amyloid Polypeptide (IAPP) |
Li et al., 2022 |
Human, synthetic, amidated C-term, wild type, no salt, thick form type 1 |
7yl3 | CryoEM |
residues:1-37 | resolution:3.2 |
|  |  |
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|
72 △ | Islet Amyloid Polypeptide (IAPP) |
Li et al., 2022 |
Human, synthetic, amidated C-term, wild type, no salt, thick form type 3 |
7yl7 | CryoEM |
residues:1-37 | resolution:3.3 |
|  |  |
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|
73 △ | Islet Amyloid Polypeptide (IAPP) S20G |
Gallardo et al., 2020 |
Human, synthetic, C-term amidated |
6zrq | cryoEM |
residues:15-37 | resolution:3.9 |
|  |  |
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|
74 △ | Islet Amyloid Polypeptide (IAPP) S20G |
Gallardo et al., 2020 |
Human, synthetic, C-term amidated |
6zrr | cryoEM |
residues:15-37 | resolution:4 |
|  |  |
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75 △ | |  |  |
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76 △ | |  |  |
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77 △ | α-synuclein |
Li et al., 2018 |
Human, recombinant, rod polymorph |
6cu7 | cryoEM |
residues:38-97 | resolution:3.5 |
|  |  |
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78 △ | |  |  |
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|
79 △ | α-synuclein |
Zhao et al., 2020b |
Human, semisynthetic, phospho-Y39, twist-dimer |
6l1t | cryoEM |
residues:1-100 | resolution:3.22 |
|  |  |
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80 △ | α-synuclein |
Zhao et al., 2020b |
Human, semisynthetic, phospho-Y39, twist-trimer |
6l1u | cryoEM |
residues:1-100 | resolution:3.37 |
|  |  |
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| Protein Information | Polarity Map | Energy Map |
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81 △ | |  |  |
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82 △ | |  |  |
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83 △ | |  |  |
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84 △ | |  |  |
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85 △ | α-synuclein |
Schweighauser et al., 2020 |
Human, extracted from Multiple System Atrophy patient brain Case 1, Type I fibril |
6xyo | cryoEM |
residues:14-99 | resolution:2.6 |
|  |  |
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|
86 △ | α-synuclein |
Schweighauser et al., 2020 |
Human, extracted from Multiple System Atrophy patient brain, Case 2, Type II-1 fibril |
6xyp | cryoEM |
residues:14-99 | resolution:3.3 |
|  |  |
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|
87 △ | α-synuclein |
Schweighauser et al., 2020 |
Human, extracted from Multiple Systems Atrophy patient brain, Case 2, Type II-2 fibril |
6xyq | cryoEM |
residues:14-99 | resolution:3.1 |
|  |  |
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|
88 △ | α-synuclein |
Long et al., 2021 |
Human, recombinant, wild type seeded with E46K hereditary mutation |
7c1d | CryoEM |
residues:46-96 | resolution:3.8 |
|  |  |
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89 △ | |  |  |
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|
90 △ | α-synuclein |
Lövestam et al., 2021 |
Human, recombinant, seeded from Multiple Systems Atrophy Case 2, Fold A, Doublet type 1 |
7nca | CryoEM |
residues:37-97 | resolution:3.47 |
|  |  |
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|
91 △ | α-synuclein |
Lövestam et al., 2021 |
Human, recombinant, seeded from Multiple Systems Atrophy Case 2, Fold A, Double type 2 |
7ncg | CryoEM |
residues:37-97 | resolution:3.43 |
|  |  |
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|
92 △ | α-synuclein |
Lövestam et al., 2021 |
Human, recombinant, seeded from Multiple Systems Atrophy Case 1, Fold B, Doublet type 1 |
7nch | CryoEM |
residues:14-91 | resolution:3.84 |
|  |  |
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|
93 △ | α-synuclein |
Lövestam et al., 2021 |
Human recombinant, seeded by Multiple Systems Atrophy Case 1, Fold B, Doublet type 2 |
7nci | CryoEM |
residues:14-91 | resolution:3.55 |
|  |  |
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|
94 △ | α-synuclein |
Lövestam et al., 2021 |
Human, recombinant, seeded by Multiple Systems Atrophy Case 1, Folds A and B, Doublet type 2 |
7ncj | CryoEM |
residues:14-91 | resolution:4.23 |
|  |  |
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|
95 △ | α-synuclein |
Lövestam et al., 2021 |
Human recombinant, seeded by Multiple Systems Atrophy Case 5, Type 3 Filaments |
7nck | CryoEM |
residues:36-99 | resolution:3.18 |
|  |  |
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|
96 △ | α-synuclein |
Frieg et al., 2022 |
Human, recombinant, seeded from brain of Parkinson's Disease Patient |
7ozg | CryoEM |
residues:14-25,36-96 | resolution:3.3 |
|  |  |
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|
97 △ | α-synuclein |
Frieg et al., 2022 |
Human, recombinant, seeded from Multiple Systems Atrophy |
7ozh | CryoEM |
residues:36-93 | resolution:3.02 |
|  |  |
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|
98 △ | α-synuclein |
Tao et al., unpublished |
Human, recombinant, recombinant, heparin-induced, polymorph 1 |
7v4a | CryoEM |
residues:14-25, 32-99 | resolution:3.2 |
|  |  |
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|
99 △ | α-synuclein |
Tao et al., unpublished |
Human, recombinant, human, recombinant, heparin-induced, polymorph 3 |
7v4b | CryoEM |
residues:14-25, 32-99 | resolution:3.1 |
|  |  |
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|
100 △ | α-synuclein |
Tao et al., unpublished |
Human, recombinant, recombinant, heparin-induced, polymorph 4 |
7v4c | CryoEM |
residues:37-98 | resolution:3.3 |
|  |  |
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| Protein Information | Polarity Map | Energy Map |
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101 △ | |  |  |
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102 △ | |  |  |
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|
103 △ | α-synuclein |
Zhao et al., 2023 |
Human, recombinant, induced by ferric iron |
7xjx | CryoEM |
residues:37-99 | resolution:2.7 |
|  |  |
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|
104 △ | α-synuclein |
Zhang et al., 2023 |
human, recombinant, non-acetylated, apo |
7yk2 | CryoEM |
residues:37-99 | resolution:2.8 |
|  |  |
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|
105 △ | α-synuclein |
Zhang et al., 2023 |
human, recombinant, non-acetylated, with dLAG3 receptor |
7yk8 | CryoEM |
residues:14-25,37-99 | resolution:2.8 |
|  |  |
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106 △ | |  |  |
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107 △ | |  |  |
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108 △ | |  |  |
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109 △ | |  |  |
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110 △ | |  |  |
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111 △ | |  |  |
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112 △ | |  |  |
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113 △ | |  |  |
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114 △ | |  |  |
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|
115 △ | |  |  |
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|
116 △ | α-synuclein |
Frieg et al., 2022 |
Human, recombinant, heparin-remodeled |
8a4l | CryoEM |
residues:14-24, 33-96 | resolution:3.22 |
|  |  |
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|
117 △ | α-synuclein |
Yang et al., 2022 |
Extracted from brain of a patient with Parkinson's Disease Dementia; fold is identical to Parkinson's Disease and Dementia with Lewy Bodies |
8a9l | CryoEM |
residues:14-22, 31-100 | resolution:2.16 |
|  |  |
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|
118 △ | α-synuclein |
Frieg et al., 2022b |
human, recombinant, Lipidic, Polymorph L2B |
8ads | CryoEM |
residues:14-24,33-96 | resolution:3.05 |
|  |  |
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|
119 △ | |  |  |
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|
120 △ | |  |  |
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|
| Protein Information | Polarity Map | Energy Map |
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121 △ | |  |  |
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|
122 △ | α-synuclein |
Frieg et al., 2022b |
human, recombinant, Lipidic, Polymorph L3A |
8aex | CryoEM |
residues:14-19,33-97 | resolution:2.76 |
|  |  |
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|
123 △ | |  |  |
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|
124 △ | α-synuclein |
Sokratian et al., 2023 |
Human, recombinant, seeded from Dementia with Lewy Bodies Case 1, Fibril Class 2b, extended pore, type 2 warp |
8cys | CryoEM |
residues:15-24,36-97 | resolution:3.1 |
|  |  |
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|
125 △ | α-synuclein |
Sokratian et al., 2023 |
Human, recombinant, seeded from Dementia with Lewy Bodies Case 1, Fibril Class 2a, extended pore, type 1 warp |
8cyt | CryoEM |
residues:15-24,36-97 | resolution:3 |
|  |  |
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|
126 △ | α-synuclein |
Sokratian et al., 2023 |
Human, recombinant, seeded from Dementia with Lewy Bodies Case 2, Fibril Class 2b, extended pore, type 1 & 2 warp |
8cyv | CryoEM |
residues:15-24,36-97 | resolution:3.5 |
|  |  |
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|
127 △ | α-synuclein |
Sokratian et al., 2023 |
Human, recombinant, seeded from Dementia with Lewy Bodies Case 3, Fibril Class 2b, compact pore, type 1 warp |
8cyw | CryoEM |
residues:14-25,36-96 | resolution:3.1 |
|  |  |
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|
128 △ | α-synuclein |
Sokratian et al., 2023 |
Human, recombinant, seeded from Dementia with Lewy Bodies Case 3, Fibril Class 2a, compact pore, type 1 warp |
8cyx | CryoEM |
residues:14-25,36-96 | resolution:3 |
|  |  |
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|
129 △ | α-synuclein |
Sokratian et al., 2023 |
Human, recombinant, seeded from Dementia with Lewy Bodies Case 5, Fibril Class 2b, extended pore, type 1 & 2 warps |
8cyy | CryoEM |
residues:15-24,36-97 | resolution:3.1 |
|  |  |
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|
130 △ | α-synuclein |
Sokratian et al., 2023 |
Human, recombinant, seeded from Dementia with Lewy Bodies Case 7, Fibril Class 2b, extended pore, type 1 warp |
8cz0 | CryoEM |
residues:15-24,36-97 | resolution:2.9 |
|  |  |
---|
|
131 △ | α-synuclein |
Sokratian et al., 2023 |
Human, recombinant, seeded from Dementia with Lewy Bodies Case 7, Fibril Class 2b, extended pore, type 2 warp |
8cz1 | CryoEM |
residues:15-24,36-97 | resolution:3 |
|  |  |
---|
|
132 △ | α-synuclein |
Sokratian et al., 2023 |
Human, recombinant, seeded from Dementia with Lewy Bodies Case 7, Fibril Class 2a, extended pore, type 1 warp |
8cz2 | CryoEM |
residues:15-24,36-97 | resolution:3 |
|  |  |
---|
|
133 △ | α-synuclein |
Sokratian et al., 2023 |
Human, recombinant, seeded from Dementia with Lewy Bodies Case 10, Fibril Class 2b, extended pore, type 1 warp |
8cz3 | CryoEM |
residues:15-24,36-97 | resolution:3.2 |
|  |  |
---|
|
134 △ | α-synuclein |
Sokratian et al., 2023 |
Human, recombinant, seeded from Dementia with Lewy Bodies Case 10, Fibril Class 2a, extended pore, type 1 warp |
8cz6 | CryoEM |
residues:15-24,36-97 | resolution:3.2 |
|  |  |
---|
|
135 △ | α-synuclein |
Dhavale et al., 2023 |
Human, recombinant, seeded with fibrils from a patient with Dementia with Lewy bodies |
8fpt | CryoEM |
residues:30-103 | resolution:100 |
|  |  |
---|
|
136 △ | α-synuclein (1-103), N-acetylated |
Ni et al., 2019 |
recombinant |
6osm | cryoEM |
residues:37-96 | resolution:3.4 |
|  |  |
---|
|
137 △ | |  |  |
---|
|
138 △ | α-synuclein (1-122), N-acetylated |
Ni et al., 2019 |
recombinant |
6osl | cryoEM |
residues:39-97 | resolution:3 |
|  |  |
---|
|
139 △ | α-synuclein (1-140), N-acetylated |
Ni et al., 2019 |
Human, recombinant |
6osj | cryoEM |
residues:37-97 | resolution:2.8 |
|  |  |
---|
|
140 △ | |  |  |
---|
|
| Protein Information | Polarity Map | Energy Map |
---|
141 △ | α-synuclein A53E |
Sun et al., 2023 |
Human, recombinant, hereditary mutation |
7uak | CryoEM |
residues:38-99 | resolution:3.38 |
|  |  |
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|
142 △ | α-synuclein A53T |
Sun et al., 2020 |
Human, recombinant, hereditary mutation |
6lrq | cryoEM |
residues:37-99 | resolution:3.5 |
|  |  |
---|
|
143 △ | |  |  |
---|
|
144 △ | |  |  |
---|
|
145 △ | α-synuclein E46K |
Zhao et al., 2020a |
Human, recombinant, hereditary mutation |
6l4s | cryoEM |
residues:45-99 | resolution:3.37 |
|  |  |
---|
|
146 △ | α-synuclein E46K |
Boyer et al., 2020 |
Human, recombinant, hereditary mutation |
6ufr | cryoEM |
residues:36-98 | resolution:2.5 |
|  |  |
---|
|
147 △ | α-synuclein G51D |
Sun et al., 2021 |
Human, recombinant, hereditary mutation |
7e0f | CryoEM |
residues:50-98 | resolution:3.02 |
|  |  |
---|
|
148 △ | α-synuclein H50Q |
Boyer et al., 2019 |
Human, recombinant, hereditary mutation |
6peo | cryoEM |
residues:36-99 | resolution:3.3 |
|  |  |
---|
|
149 △ | α-synuclein H50Q |
Boyer et al., 2019 |
Human, recombinant, hereditary mutation |
6pes | cryoEM |
residues:36-99 | resolution:3.6 |
|  |  |
---|
|
150 △ | α-synuclein, human |
Fan et al., 2023 |
Recombinant, seeded from a Parkinson's Disease patient, preclinical, filament type 1A |
7v47 | CryoEM |
residues:36-96 | resolution:2.8 |
|  |  |
---|
|
151 △ | α-synuclein, human |
Fan et al., 2023 |
Recombinant, seeded from a Parkinson's Disease patient, postmortem, filament type 1D |
7v48 | CryoEM |
residues:36-98 | resolution:3 |
|  |  |
---|
|
152 △ | α-synuclein, human |
Fan et al., 2023 |
Recombinant, seeded from a Parkinson's Disease patient, postmortem, filament type 4 |
7v49 | CryoEM |
residues:36-95 | resolution:3.4 |
|  |  |
---|
|
153 △ | α-synuclein, human |
Fan et al., 2023 |
Recombinant, seeded from a Parkinson's Disease patient, mid-to-late stage 1, minor polymorph |
7xo0 | CryoEM |
residues:36-97 | resolution:3 |
|  |  |
---|
|
154 △ | α-synuclein, human |
Fan et al., 2023 |
Recombinant, seeded from a Parkinson's Disease patient, mid-to-late stage 1, major polymorph |
7xo1 | CryoEM |
residues:37-97 | resolution:3 |
|  |  |
---|
|
155 △ | α-synuclein, human |
Fan et al., 2023 |
Recombinant, seeded from a Parkinson's Disease patient, mid-to-late stage 4, minor polymorph |
7xo2 | CryoEM |
residues:36-97 | resolution:3 |
|  |  |
---|
|
156 △ | α-synuclein, human |
Fan et al., 2023 |
Recombinant, seeded from a Parkinson's Disease patient, mid-to-late stage 4, filament type 1C |
7xo3 | CryoEM |
residues:36-98 | resolution:2.6 |
|  |  |
---|
|
157 △ | α-synuclein, human |
Fan et al., 2023 |
Recombinant, seeded from a Parkinson's Disease patient, preclinical, major polymorph |
8h03 | CryoEM |
residues:36-96 | resolution:2.8 |
|  |  |
---|
|
158 △ | α-synuclein, human |
Fan et al., 2023 |
Recombinant, seeded from a Parkinson's Disease patient, postmortem, major polymorph |
8h04 | CryoEM |
residues:36-98 | resolution:3 |
|  |  |
---|
|
159 △ | α-synuclein, human |
Fan et al., 2023 |
Recombinant, seeded from a Parkinson's Disease patient, postmortem, minor polymorph |
8h05 | CryoEM |
residues:36-95 | resolution:3.4 |
|  |  |
---|
|
160 △ | α-synuclein, human, mixture of wild type and MAAAEKT insertion after residue 22 |
Yang et al., 2023 |
Extracted from Juvenile-Onset Synucleinopathy patient brain, singlet filament |
8bqv | CryoEM |
residues:14-25,36-100 | resolution:2 |
|  |  |
---|
|
| Protein Information | Polarity Map | Energy Map |
---|
161 △ | α-synuclein, human, mixture of wild type and MAAAEKT insertion after residue 22 |
Yang et al., 2023 |
Extracted from Juvenile-Onset Synucleinopathy patient brain, doublet filament |
8bqw | CryoEM |
residues:14-25,36-100 | resolution:2.3 |
|  |  |
---|
|
162 △ | α-synuclein, human, mixture of wild type and MAAAEKT insertion after residue 22 |
Yang et al., 2023 |
Human, recombinant, type 1 filaments |
8ce7 | CryoEM |
residues:37-99 | resolution:2.7 |
|  |  |
---|
|
163 △ | α-synuclein, human, mixture of wild type and MAAAEKT insertion after residue 22 |
Yang et al., 2023 |
Human, recombinant, type 2 filament |
8ceb | CryoEM |
residues:40-97 | resolution:2.7 |
|  |  |
---|
|
164 △ | |  |  |
---|
|
165 △ | |  |  |
---|
|
166 △ | |  |  |
---|
|
167 △ | |  |  |
---|
|
168 △ | |  |  |
---|
|
169 △ | |  |  |
---|
|
170 △ | |  |  |
---|
|
171 △ | |  |  |
---|
|
172 △ | |  |  |
---|
|
173 △ | |  |  |
---|
|
174 △ | |  |  |
---|
|
175 △ | |  |  |
---|
|
176 △ | |  |  |
---|
|
177 △ | Prion Protein, hamster |
Chen et al., 2022 |
Recombinant, prepared in acidic solution |
7yat | CryoEM |
residues:119-143 | resolution:2.2 |
|  |  |
---|
|
178 △ | Prion Protein, hamster Syrian |
Kraus et al., 2021 |
Extracted from clinically ill hamster brain, 263K prion strain, infectious |
7lna | CryoEM |
residues:95-227 | resolution:3.14 |
|  |  |
---|
|
179 △ | |  |  |
---|
|
180 △ | Prion Protein, human |
Hallinan et al., 2022 |
Extracted from patient with Gerstmann-Straussler-Scheinker disease, type I filament |
7umq | CryoEM |
residues:80-141 | resolution:3.29 |
|  |  |
---|
|
| Protein Information | Polarity Map | Energy Map |
---|
181 △ | Prion Protein, human |
Hallinan et al., 2022 |
Extracted from patient with Gerstmann-Straussler-Scheinker disease, type IIb filament |
7un5 | CryoEM |
residues:80-141 | resolution:3.13 |
|  |  |
---|
|
182 △ | Prion Protein, human, E196K mutation |
Wang et al., 2021 |
Recombinant |
7dwv | CryoEM |
residues:175-217 | resolution:3.07 |
|  |  |
---|
|
183 △ | Prion Protein, human, M129 variant, (94-178) |
Glynn et al., 2020 |
Recombinant |
6uur | cryoEM |
residues:106-145 | resolution:3.5 |
|  |  |
---|
|
184 △ | Prion Protein, human, Y145Stop Mutation |
Li et al., 2022 |
Recombinant |
7rl4 | CryoEM |
residues:108-141 | resolution:2.86 |
|  |  |
---|
|
185 △ | Prion Protein, mouse |
Manka et al., 2022 |
Extracted from brains of a terminally ill mouse, anchorless, aRML prion strain, infectious |
7qig | CryoEM |
residues:94-225 | resolution:2.7 |
|  |  |
---|
|
186 △ | Prion Protein, mouse |
Hoyt et al., 2022 |
Extracted from brains of terminally ill mice, anchorless, aRML prion strain, infectious |
7td6 | CryoEM |
residues:93-230 | resolution:3 |
|  |  |
---|
|
187 △ | Prion Protein, mouse |
Manka et al., 2023 |
Extracted from brains of a terminally ill mouse, ME7 prion strain, infectious |
8a00 | CryoEM |
residues:94-229 | resolution:2.6 |
|  |  |
---|
|
188 △ | Prion Protein, mouse |
Hoyt et al., 2022b |
Extracted from brains of terminally ill mice, a22L prion strain, infectious |
8efu | CryoEM |
residues:94-226 | resolution:3.2 |
|  |  |
---|
|
189 △ | Prion Protein, mouse, PrP23-144 |
Li et al., 2022 |
Recombinant |
8dja | CryoEM |
residues:108-141 | resolution:3.92 |
|  |  |
---|
|
190 △ | |  |  |
---|
|
191 △ | |  |  |
---|
|
192 △ | |  |  |
---|
|
193 △ | |  |  |
---|
|
194 △ | Serum Amyloid A, feline |
Schulte et al., 2022 |
Extracted from a short hair cat with AA amyloidosis, kidney |
7zh7 | CryoEM |
residues:19-94 | resolution:3.3 |
|  |  |
---|
|
195 △ | Serum Amyloid A, human |
Liberta et al., 2019 |
Extracted from AA amyloidosis patient kidney, glomerular variant |
6mst | cryoEM |
residues:2-55 | resolution:2.7 |
|  |  |
---|
|
196 △ | Serum Amyloid A, human |
Banerjee et al., 2022 |
Extracted from an AA amyloidosis patient kidney, vascular variant |
7zky | CryoEM |
residues:2-69 | resolution:2.56 |
|  |  |
---|
|
197 △ | Serum Amyloid A, mouse |
Liberta et al., 2019 |
Extracted from spleen of a mouse with systemic AA amyloidosis, fibril morphology I |
6dso | cryoEM |
residues:1-69 | resolution:3 |
|  |  |
---|
|
198 △ | Serum Amyloid A, mouse |
Bansal et al., 2021 |
Recombinant, fibril morphology i |
6zcf | cryoEM |
residues:1-37 | resolution:2.73 |
|  |  |
---|
|
199 △ | Serum Amyloid A, mouse |
Bansal et al., 2021 |
Recombinant, fibril morphology ii |
6zcg | cryoEM |
residues:1-37 | resolution:2.95 |
|  |  |
---|
|
200 △ | Serum Amyloid A, mouse |
Bansal et al., 2021 |
Extracted from spleen of a mouse with systemic AA amyloidosis, fibril morphology II |
6zch | cryoEM |
residues:1-69 | resolution:3.5 |
|  |  |
---|
|
| Protein Information | Polarity Map | Energy Map |
---|
201 △ | Serum Amyloid A, mouse |
Heerde et al., 2022 |
Recombinant, seeded by ex vivo fibrils from mouse liver, fibril morphology I |
7ovt | CryoEM |
residues:1-69 | resolution:2.69 |
|  |  |
---|
|
202 △ | |  |  |
---|
|
203 △ | Superoxide Dismutase |
Wang et al., 2022 |
Human, recombinant, full-length |
7vzf | CryoEM |
residues:3-55, 86-153 | resolution:2.93 |
|  |  |
---|
|
204 △ | |  |  |
---|
|
205 △ | |  |  |
---|
|
206 △ | Tau (244-391) |
Lövestam et al., 2022 |
Human, recombinant, tetrasodium pyrophosphate, filament type 20a |
7ql2 | CryoEM |
residues:275-324 | resolution:2.95 |
|  |  |
---|
|
207 △ | Tau (258-391) |
Lövestam et al., 2022 |
Human, recombinant, shaken at 700 rpm, filament type 38a |
7qk3 | CryoEM |
residues:270-330 | resolution:2.44 |
|  |  |
---|
|
208 △ | Tau (258-391) |
Lövestam et al., 2022 |
Human, recombinant, heparan sulfate, 700 rpm, filament type 40a |
7qk6 | CryoEM |
residues:275-328 | resolution:2.26 |
|  |  |
---|
|
209 △ | Tau (258-391) |
Lövestam et al., 2022 |
Human, recombinant, phosphoglycerate, 700 rpm, filament type 39a |
7qkg | CryoEM |
residues:275-328 | resolution:3.36 |
|  |  |
---|
|
210 △ | Tau (258-391) |
Lövestam et al., 2022 |
Human, recombinant, sodium azide, filament type 41a |
7qkh | CryoEM |
residues:277-317 | resolution:3.17 |
|  |  |
---|
|
211 △ | Tau (258-391) |
Lövestam et al., 2022 |
Human, recombinant, phosphoglycerate, shaken at 700rpm, filament type 39a |
7qkk | CryoEM |
residues:304-379 | resolution:2.8 |
|  |  |
---|
|
212 △ | Tau (263-280) acetylated K274 and K280 |
Li et al., 2023 |
Human, synthetic |
8fnz | CryoEM |
residues:263-280 | resolution:3.88 |
|  |  |
---|
|
213 △ | Tau (266-391) |
Lövestam et al., 2022 |
Human, recombinant, CTE-like fold, phosphate-buffered saline, filament type 23a |
7ql1 | CryoEM |
residues:306-378 | resolution:3.34 |
|  |  |
---|
|
214 △ | Tau (266-391) and 3R/(297-391) |
Li et al., 2022 |
Human, Recombinant, PHF-like polymorph |
7ymn | CryoEM |
residues:304-379 | resolution:3.46 |
|  |  |
---|
|
215 △ | Tau (266-391) S356D |
Lövestam et al., 2022 |
Human, recombinant, KCl, filament type 44a |
7qkw | CryoEM |
residues:275-328 | resolution:2.32 |
|  |  |
---|
|
216 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, LiCl, filament type 9a |
7qjy | CryoEM |
residues:305-379 | resolution:3.14 |
|  |  |
---|
|
217 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, LiCl, filament type 9b |
7qjz | CryoEM |
residues:305-378 | resolution:3.4 |
|  |  |
---|
|
218 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, KCl, filament type 10a |
7qk5 | CryoEM |
residues:306-379 | resolution:1.92 |
|  |  |
---|
|
219 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, Copper(II) chloride, filament type 12a |
7qkf | CryoEM |
residues:305-360 | resolution:2.83 |
|  |  |
---|
|
220 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, magnesium chloride, NaCl, filament type 14b |
7qkj | CryoEM |
residues:305-379 | resolution:3.26 |
|  |  |
---|
|
| Protein Information | Polarity Map | Energy Map |
---|
221 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, zinc chloride, filament type 11a |
7qkl | CryoEM |
residues:304-379 | resolution:2.07 |
|  |  |
---|
|
222 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, MgCl2 and NaCl, filament type 14a |
7qku | CryoEM |
residues:304-379 | resolution:2.57 |
|  |  |
---|
|
223 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, CTE-like fold, MgSO4, NaCl, filament type 15a |
7qkv | CryoEM |
residues:309-377 | resolution:3.23 |
|  |  |
---|
|
224 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, CTE-like fold, MgSO4, NaCl, filament type 15b |
7qkx | CryoEM |
residues:306-378 | resolution:3.16 |
|  |  |
---|
|
225 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, CTE-like fold, MgSO4, NaCl, filament type 15c |
7ql0 | CryoEM |
residues:306-378 | resolution:3.13 |
|  |  |
---|
|
226 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, NaCl, filament type 8b |
7ql3 | CryoEM |
residues:308-378 | resolution:3.32 |
|  |  |
---|
|
227 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, sodium bicarbonate, NaCl, filament type 16a |
7r4t | CryoEM |
residues:304-379 | resolution:2.73 |
|  |  |
---|
|
228 △ | Tau (266-391)(297-391) |
Lövestam et al., 2022 |
Human, recombinant, KCl, filament type 10b |
7r5h | CryoEM |
residues:305-388 | resolution:2.59 |
|  |  |
---|
|
229 △ | Tau (266-391), S356D |
Lövestam et al., 2022 |
Human, recombinant, NaCl, filament type 45a |
7qkm | CryoEM |
residues:274-328 | resolution:2.66 |
|  |  |
---|
|
230 △ | Tau (297-391) |
Lövestam et al., 2022 |
Human, recombinant, AD-like fold, LiCl, filament type 2c |
7qjv | CryoEM |
residues:304-378 | resolution:3.29 |
|  |  |
---|
|
231 △ | Tau (297-391) |
Lövestam et al., 2022 |
Human, recombinant, CTE type II-like polymorph, filament type 8a |
7qjw | CryoEM |
residues:305-379 | resolution:2.81 |
|  |  |
---|
|
232 △ | Tau (297-391) |
Lövestam et al., 2022 |
Human, recombinant, shaken at 700 rpm, filament type 34b |
7qjx | CryoEM |
residues:304-378 | resolution:2.99 |
|  |  |
---|
|
233 △ | Tau (297-391) |
Lövestam et al., 2022 |
Human, recombinant, PHF-like polymorph, 200 mM MgCl2, 200 rpm, filament type 4a |
7ql4 | CryoEM |
residues:304-379 | resolution:3.2 |
|  |  |
---|
|
234 △ | Tau (297-391) |
Li et al., 2022 |
Human, Recombinant, spindle-like fold |
7ypg | CryoEM |
residues:304-362 | resolution:2.54 |
|  |  |
---|
|
235 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, First Intermediate Amyloid (FIA) on pathway to AD and CTE folds |
8ppo | CryoEM |
residues:302-316 | resolution:2 |
|  |  |
---|
|
236 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA1 |
8q27 | CryoEM |
residues:303-379 | resolution:2.02 |
|  |  |
---|
|
237 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA2 |
8q2j | CryoEM |
residues:303-380 | resolution:3.23 |
|  |  |
---|
|
238 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA3 |
8q2k | CryoEM |
residues:305-379 | resolution:2.88 |
|  |  |
---|
|
239 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA5 |
8q7f | CryoEM |
residues:304-378 | resolution:3.72 |
|  |  |
---|
|
240 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA6 |
8q7l | CryoEM |
residues:306-379 | resolution:2.82 |
|  |  |
---|
|
| Protein Information | Polarity Map | Energy Map |
---|
241 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA7 |
8q7m | CryoEM |
residues:304-379 | resolution:3.26 |
|  |  |
---|
|
242 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA8 |
8q7p | CryoEM |
residues:304-378 | resolution:3.28 |
|  |  |
---|
|
243 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA11 |
8q7t | CryoEM |
residues:304-378 | resolution:3 |
|  |  |
---|
|
244 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Late Intermediate Amyloid on Pathway to AD fold, AD-LIA2 |
8q88 | CryoEM |
residues:304-379 | resolution:2.95 |
|  |  |
---|
|
245 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Middle Intermediate Amyloid on Pathway to AD fold, AD-MIA10 |
8q8c | CryoEM |
residues:304-378 | resolution:1.92 |
|  |  |
---|
|
246 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Late Intermediate Amyloid on Pathway to AD fold, AD-LIA6 |
8q8d | CryoEM |
residues:304-379 | resolution:3.04 |
|  |  |
---|
|
247 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Late Intermediate Amyloid on Pathway to CTE fold, CTE-LIA3 |
8q9f | CryoEM |
residues:305-379 | resolution:1.91 |
|  |  |
---|
|
248 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Late Intermediate Amyloid on Pathway to CTE fold, CTE-LIA5 |
8q9g | CryoEM |
residues:306-378 | resolution:2.65 |
|  |  |
---|
|
249 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Late Intermediate Amyloid on Pathway to CTE fold, CTE-LIA6 |
8q9i | CryoEM |
residues:306-378 | resolution:2.56 |
|  |  |
---|
|
250 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Late Intermediate Amyloid on Pathway to CTE fold, CTE-LIA7 |
8q9j | CryoEM |
residues:306-378 | resolution:2.96 |
|  |  |
---|
|
251 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Late Intermediate Amyloid on Pathway to CTE fold, CTE-LIA13 |
8q9k | CryoEM |
residues:306-379 | resolution:3.2 |
|  |  |
---|
|
252 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Late Intermediate Amyloid on Pathway to CTE fold, CTE-LIA14 |
8q9l | CryoEM |
residues:306-378 | resolution:2.76 |
|  |  |
---|
|
253 △ | |  |  |
---|
|
254 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, CTE fold type II (CTE-II-like) |
8q9o | CryoEM |
residues:305-379 | resolution:3.1 |
|  |  |
---|
|
255 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Late Intermediate Amyloid on Pathway to AD fold, AD-LIA8 |
8qcp | CryoEM |
residues:304-379 | resolution:3.21 |
|  |  |
---|
|
256 △ | Tau (297-391) |
Lövestam et al., 2023 |
Human, recombinant, Middle Intermediate Amyloid on Pathway to CTE fold, CTE-MIA12 |
8qcr | CryoEM |
residues:305-379 | resolution:2.75 |
|  |  |
---|
|
257 △ | Tau (297-394) |
Lövestam et al., 2022 |
Human, recombinant, phosphate buffered saline, filament type 35d |
7qk1 | CryoEM |
residues:305-379 | resolution:3.03 |
|  |  |
---|
|
258 △ | Tau (297-408) S396D, S400D, T403D |
Lövestam et al., 2022 |
Human, recombinant, AD-like fold, filament type 42a |
7qki | CryoEM |
residues:304-379 | resolution:3.13 |
|  |  |
---|
|
259 △ | Tau (300-391) |
Lövestam et al., 2022 |
Human, recombinant, phosphate buffered saline, filament type 36a |
7qk2 | CryoEM |
residues:308-378 | resolution:2.61 |
|  |  |
---|
|
260 △ | |  |  |
---|
|
| Protein Information | Polarity Map | Energy Map |
---|
261 △ | Tau 0N4R with phosphoserine |
Lövestam et al., 2022 |
Human, recombinant, filament type 47a |
7qky | CryoEM |
residues:376-441 | resolution:1.83 |
|  |  |
---|
|
262 △ | |  |  |
---|
|
263 △ | Tau 3R |
Falcon et al., 2018 |
Human, extracted from brain of a Pick's Disease patient, Pick fold |
6gx5 | cryoEM |
residues:254-274, 306-378 | resolution:3.2 |
|  |  |
---|
|
264 △ | Tau 3R |
Zhang et al., 2019 |
human, recombinant, heparin Induced |
6qjq | cryoEM |
residues:272-330 Δ275-305 | resolution:3.5 |
|  |  |
---|
|
265 △ | Tau 3R |
Tarutani et al., 2023 |
Extracted from human SH-SY5Y cell culture, seeded with brain of a patient with Alzheimers Disease |
8ore | CryoEM |
residues:273-274,306-380 | resolution:2.5 |
|  |  |
---|
|
266 △ | Tau 3R |
Schweighauser et al., 2023 |
Human, extracted from brain of a patient with Pick's Disease and MAPT ΔK281 mutation |
8p34 | CryoEM |
residues:254-274, 306-378 | resolution:2.61 |
|  |  |
---|
|
267 △ | Tau 3R and 4R |
Fitzpatrick et al., 2017 |
Human, extracted from Alzheimer patient brain, Paired Helical Filament |
5o3l | cryoEM |
residues:306-378 | resolution:3.4 |
|  |  |
---|
|
268 △ | Tau 3R and 4R |
Fitzpatrick et al., 2017 |
Human, extracted from Alzheimers patient brain, Straight Filament |
5o3t | cryoEM |
residues:306-378 | resolution:3.4 |
|  |  |
---|
|
269 △ | Tau 3R and 4R |
Hallinan et al., 2021 |
Human, extracted from PrP Cerebral Amyloid Angiopathy Patient Brain, Paired Helical Filament |
7mkf | CryoEM |
residues:306-378 | resolution:3 |
|  |  |
---|
|
270 △ | Tau 3R and 4R |
Hallinan et al., 2021 |
Human, extracted from PrP Cerebral Amyloid Angiopathy Patient Brain, Straight Filament |
7mkg | CryoEM |
residues:306-378 | resolution:3.07 |
|  |  |
---|
|
271 △ | Tau 3R and 4R |
Hallinan et al., 2021 |
Human, extracted from Gerstmann-Sträussler-Scheinker Patient Brain, Paired Helical Filament |
7mkh | CryoEM |
residues:305-379 | resolution:3.3 |
|  |  |
---|
|
272 △ | Tau 3R and 4R |
Shi et al., 2021 |
Human, extracted from Primary Age-Related Tauopathy Patient Brain, Case 3, Paired Helical Filament |
7nrq | CryoEM |
residues:304-380 | resolution:2.76 |
|  |  |
---|
|
273 △ | Tau 3R and 4R |
Shi et al., 2021 |
Human, extracted from Primary Age-Related Tauopathy Patient Brain, Case 3, Straight Filament Conformation 1 |
7nrs | CryoEM |
residues:304-380 | resolution:2.68 |
|  |  |
---|
|
274 △ | Tau 3R and 4R |
Shi et al., 2021 |
Human, extracted from Primary Age-Related Tauopathy Patient Brain, Case 3, Straight Filament Conformation 2 |
7nrt | CryoEM |
residues:304-380 | resolution:2.68 |
|  |  |
---|
|
275 △ | Tau 3R and 4R |
Shi et al., 2021 |
Human, extracted from Alzheimers Patient Brain and Stained with PET ligand APN1607, Paired Helical Filament |
7nrv | CryoEM |
residues:304-380 | resolution:3 |
|  |  |
---|
|
276 △ | Tau 3R and 4R |
Shi et al., 2021 |
Human, extracted from Alzheimers Patient Brain and Stained with PET ligand APN1607, Straight Filament |
7nrx | CryoEM |
residues:304-380 | resolution:3.55 |
|  |  |
---|
|
277 △ | Tau 3R and 4R |
Seidler et al., 2022 |
Human, extracted from Alzheimers Patient Brain and soaked with EGCG for 0 hours |
7upe | CryoEM |
residues:304-379 | resolution:3.4 |
|  |  |
---|
|
278 △ | Tau 3R and 4R |
Seidler et al., 2022 |
Human, extracted from Alzheimers Patient Brain and soaked with EGCG for 1 hour |
7upf | CryoEM |
residues:306-379 | resolution:3.3 |
|  |  |
---|
|
279 △ | Tau 3R and 4R |
Seidler et al., 2022 |
Human, extracted from Alzheimers Patient Brain and soaked with EGCG for 3 hours |
7upg | CryoEM |
residues:306-379 | resolution:3.8 |
|  |  |
---|
|
280 △ | Tau 3R and 4R |
Stern et al., 2023 |
Human, extracted from Alzheimers patient brain, Paired Helical Filament, aqueous fraction |
8azu | CryoEM |
residues:306-379 | resolution:3.1 |
|  |  |
---|
|
| Protein Information | Polarity Map | Energy Map |
---|
281 △ | Tau 3R and 4R |
Fowler et al., 2023 |
Human, extracted from Alzheimers patient brain, Paired Helical Filament, extracellular vesicle fraction |
8bgs | CryoEM |
residues:305-379 | resolution:3.16 |
|  |  |
---|
|
282 △ | Tau 3R and 4R |
Fowler et al., 2023 |
Human, extracted from Alzheimers patient brain, Paired Helical Filament, cellular fraction |
8bgv | CryoEM |
residues:305-379 | resolution:3.27 |
|  |  |
---|
|
283 △ | Tau 3R and 4R |
Merz et al., 2023 |
Human, extracted from Alzheimers Patient Brain and Stained with PET ligand GTP-1, Paired Helical Filament |
8fug | CryoEM |
residues:306-378 | resolution:2.7 |
|  |  |
---|
|
284 △ | Tau 4R |
Falcon et al., 2019 |
Human, extracted from Chronic Traumatic Encephalopathy patient brain, filament CTE Type 1 |
6nwp | cryoEM |
residues:305-379 | resolution:2.3 |
|  |  |
---|
|
285 △ | Tau 4R |
Falcon et al., 2019 |
Human, extracted from Chronic Traumatic Encephalopathy patient brain, filament CTE Type 2 |
6nwq | cryoEM |
residues:305-379 | resolution:3.4 |
|  |  |
---|
|
286 △ | Tau 4R |
Zhang et al., 2019 |
Human, recombinant, heparin induced, Snake Polymorph |
6qjh | cryoEM |
residues:272-330 | resolution:3.3 |
|  |  |
---|
|
287 △ | Tau 4R |
Zhang et al., 2019 |
Human, recombinant, heparin induced, Twister Polymorph |
6qjm | cryoEM |
residues:274-292, 304-321 | resolution:3.3 |
|  |  |
---|
|
288 △ | Tau 4R |
Zhang et al., 2019 |
Human, recombinant, heparin induced, Jagged Polymorph |
6qjp | cryoEM |
residues:274-290, 304-321 | resolution:3.5 |
|  |  |
---|
|
289 △ | Tau 4R |
Zhang et al., 2020 |
Human, extracted from brain of Corticobasal Degeneration patient, filament CBD Type 1 |
6tjo | cryoEM |
residues:274-380 | resolution:3.2 |
|  |  |
---|
|
290 △ | Tau 4R |
Zhang et al., 2020 |
Human, extracted from brain of Corticobasal Degeneration patient, filament CBD Type 2 |
6tjx | cryoEM |
residues:274-380 | resolution:3 |
|  |  |
---|
|
291 △ | Tau 4R |
Shi et al., 2021 |
Human, extracted from Progressive Supranuclear Palsy Patient Brain, PSP Filament |
7p65 | CryoEM |
residues:272-381 | resolution:2.7 |
|  |  |
---|
|
292 △ | Tau 4R |
Shi et al., 2021 |
Extracted from Globular Glial Tauopathy Patient Brain, Filament GGT Type 1 |
7p66 | CryoEM |
residues:272-379 | resolution:3 |
|  |  |
---|
|
293 △ | Tau 4R |
Shi et al., 2021 |
Extracted from Globular Glial Tauopathy Patient Brain, Filament GGT Type 2 |
7p67 | CryoEM |
residues:272-379 | resolution:3.1 |
|  |  |
---|
|
294 △ | Tau 4R |
Shi et al., 2021 |
Human, extracted from Globular Glial Tauopathy (GGT) Patient Brain, Filament Type 3 |
7p68 | CryoEM |
residues:272-379 | resolution:2.87 |
|  |  |
---|
|
295 △ | Tau 4R |
Shi et al., 2021 |
Human, extracted from Globular Glial Tauopathy Patient Brain, Filament GGT Type 3 |
7p6a | CryoEM |
residues:272-379 | resolution:1.9 |
|  |  |
---|
|
296 △ | Tau 4R |
Shi et al., 2021 |
Human, extracted from Limbic-Predominant Neuronal Inclusion Body 4R Tauopathy Patient Brain, Filament LNT Type 1b |
7p6b | CryoEM |
residues:272-379 | resolution:2.5 |
|  |  |
---|
|
297 △ | Tau 4R |
Shi et al., 2021 |
Human, extracted from Limbic-Predominant Neuronal Inclusion Body 4R Tauopathy Patient Brain, Filament LNT Type 2 |
7p6c | CryoEM |
residues:272-379 | resolution:2.2 |
|  |  |
---|
|
298 △ | Tau 4R |
Shi et al., 2021 |
Human, extracted from Argyrophilic Grain Disease Patient Brain, AGD Filament Type 1 |
7p6d | CryoEM |
residues:273-387 | resolution:3.3 |
|  |  |
---|
|
299 △ | Tau 4R |
Shi et al., 2021 |
Human, extracted from Argyrophilic Grain Disease Patient Brain, AGD Filament Type 2 |
7p6e | CryoEM |
residues:274-381 | resolution:3.4 |
|  |  |
---|
|
300 △ | Tau 4R |
Chang et al., 2022 |
Human, extracted from Progressive Supranuclear Palsy (PSP) Patient Brain, Case 1 |
7u0z | CryoEM |
residues:272-381 | resolution:4.2 |
|  |  |
---|
|
| Protein Information | Polarity Map | Energy Map |
---|
301 △ | Tau 4R |
Shi et al., 2022 |
Human, extracted from Chronic Traumatic Encephalopathy patient brain, filament CTE Type 1, complex with PET ligand flortaucipir |
8byn | CryoEM |
residues:305-379 | resolution:2.6 |
|  |  |
---|
|
302 △ | Tau 4R |
Tarutani et al., 2023 |
Extracted from human SH-SY5Y cell culture, seeded with brain of a patient with Corticobasal Degeneration, Filament Type I |
8orf | CryoEM |
residues:277-377 | resolution:2.5 |
|  |  |
---|
|
303 △ | Tau 4R |
Tarutani et al., 2023 |
Extracted from human SH-SY5Y cell culture, seeded with brain of a patient with Corticobasal Degeneration, Filament Type II |
8org | CryoEM |
residues:277-362 | resolution:2.3 |
|  |  |
---|
|
304 △ | TDP-43 |
Arseni et al., 2021 |
Human, extracted from patient with Amyotrophic Lateral Sclerosis and Fronto-Temporal Lobar Degeneration type B |
7py2 | CryoEM |
residues:282-360 | resolution:2.59 |
|  |  |
---|
|
305 △ | TDP-43 |
Arseni et al., 2023 |
Human, extracted from patient with Fronto-temporal Lobar Degeneration type A, filament block variant 1 |
8cg3 | CryoEM |
residues:272-360 | resolution:2.39 |
|  |  |
---|
|
306 △ | TDP-43 |
Arseni et al., 2023 |
Human, extracted from Patient with Fronto-temporal Lobar Degeneration type A, filament block variant 2 |
8cgg | CryoEM |
residues:281-360 | resolution:2.5 |
|  |  |
---|
|
307 △ | TDP-43 |
Arseni et al., 2023 |
Human, extracted from patient with Fronto-temporal Lobar Degeneration type A, filament block variant 3 |
8cgh | CryoEM |
residues:281-360 | resolution:2.68 |
|  |  |
---|
|
308 △ | |  |  |
---|
|
309 △ | TDP-43 (279-360) |
Kumar et al., 2023 |
Human, recombinant, singlet fibril |
7q3u | CryoEM |
residues:281-351 | resolution:3.7 |
|  |  |
---|
|
310 △ | |  |  |
---|
|
311 △ | |  |  |
---|
|
312 △ | |  |  |
---|
|
313 △ | |  |  |
---|
|
314 △ | TDP-43 Low Complexity Domain (267-414) |
Li et al., 2021 |
recombinant |
7kwz | cryoEM |
residues:276-414 | resolution:3.2 |
|  |  |
---|
|
315 △ | |  |  |
---|
|
316 △ | TMEM106B |
Schweighauser et al., 2022 |
Extracted from Patient with Multiple Systems Atrophy, case 18, fibril fold I-d |
7qvf | CryoEM |
residues:120-254 | resolution:3.64 |
|  |  |
---|
|
317 △ | TMEM106B |
Schweighauser et al., 2022 |
Human, extracted from Patient with Multiple Systems Atrophy, case 19, filament fold II-a |
7qwg | CryoEM |
residues:120-254 | resolution:3.38 |
|  |  |
---|
|
318 △ | TMEM106B |
Schweighauser et al., 2022 |
Human, extracted from Patient with Multiple Systems Atrophy, case 19, filament fold II-b |
7qwl | CryoEM |
residues:120-254 | resolution:3.47 |
|  |  |
---|
|
319 △ | TMEM106B |
Schweighauser et al., 2022 |
Human, extracted from Patient with Multiple Systems Atrophy, case 17, filament fold III |
7qwm | CryoEM |
residues:120-254 | resolution:2.76 |
|  |  |
---|
|
320 △ | TMEM106B |
Jiang et al., 2022 |
Human, extracted from Patient with Fronto-temporal Lobar Degeneration, Type C, fibril polymorph 1 |
7saq | CryoEM |
residues:120-254 | resolution:2.9 |
|  |  |
---|
|
| Protein Information | Polarity Map | Energy Map |
---|
321 △ | TMEM106B |
Jiang et al., 2022 |
Human, extracted from patient with Fronto-temporal Lobar Degeneration, Type C, fibril polymorph 2 |
7sar | CryoEM |
residues:120-254 | resolution:3.2 |
|  |  |
---|
|
322 △ | TMEM106B |
Jiang et al., 2022 |
Human, extracted from brain of a patient with Fronto-temporal Lobar Degeneration Type C, Fibril polymorph 3 |
7sas | CryoEM |
residues:120-254 | resolution:3.7 |
|  |  |
---|
|
323 △ | TMEM106B |
Chang et al., 2022 |
Human, extracted from Patient with Progressive Supranuclear Palsy, case 2, singlet filament |
7u10 | CryoEM |
residues:120-254 | resolution:3 |
|  |  |
---|
|
324 △ | TMEM106B |
Chang et al., 2022 |
Human, extracted from patient with Fronto-temporal Lobar Degeneration, Type A, case 1, singlet filament |
7u11 | CryoEM |
residues:120-254 | resolution:3.2 |
|  |  |
---|
|
325 △ | TMEM106B |
Chang et al., 2022 |
Human, extracted from patient with Fronto-temporal Lobar Degeneration, Type A, case 2, singlet filament |
7u12 | CryoEM |
residues:120-254 | resolution:3.5 |
|  |  |
---|
|
326 △ | TMEM106B |
Chang et al., 2022 |
Human, extracted from patient with Fronto-temporal Lobar Degeneration, Type A, case 4, singlet filament |
7u13 | CryoEM |
residues:120-254 | resolution:2.9 |
|  |  |
---|
|
327 △ | TMEM106B |
Chang et al., 2022 |
Human, extracted from patient with Fronto-temporal Lobar Degeneration, Type C, case 8, singlet filament |
7u14 | CryoEM |
residues:120-254 | resolution:4.5 |
|  |  |
---|
|
328 △ | TMEM106B |
Chang et al., 2022 |
Human, extracted from Patient with Fronto-temporal Lobar Degeneration, Type B, case 7, singlet filament |
7u15 | CryoEM |
residues:120-254 | resolution:3 |
|  |  |
---|
|
329 △ | TMEM106B |
Chang et al., 2022 |
Human, extracted from Patient with Fronto-temporal Lobar Degeneration, Type A, all cases combined, singlet filament |
7u16 | CryoEM |
residues:120-254 | resolution:2.7 |
|  |  |
---|
|
330 △ | TMEM106B |
Chang et al., 2022 |
Human, extracted from Patient with Fronto-temporal Lobar Degeneration, Type B, all cases combined, singlet filament |
7u17 | CryoEM |
residues:120-254 | resolution:3 |
|  |  |
---|
|
331 △ | TMEM106B |
Chang et al., 2022 |
Human, extracted from Patient with Fronto-temporal Lobar Degeneration, Type A, all cases combined |
7u18 | CryoEM |
residues:120-254 | resolution:2.7 |
|  |  |
---|
|
332 △ | TMEM106B |
Fan et al., 2022 |
Human, extracted from brain of 101 year old human with no diagnosed disease |
7x83 | CryoEM |
residues:120-254 | resolution:3.4 |
|  |  |
---|
|
333 △ | TMEM106B |
Fan et al., 2022 |
Human, extracted from brain of patient with Parkinsons Disease Dementia |
7x84 | CryoEM |
residues:120-254 | resolution:3 |
|  |  |
---|
|
334 △ | Transforming Growth Factor Beta Induced Protein, TGFBIp(611-633), G623R |
Low et al., 2023 |
Human, recombinant |
8hia | CryoEM |
residues:611-633 | resolution:4.9 |
|  |  |
---|
|
335 △ | Transthyretin |
Steinebrei et al., 2022 |
Human, wild type, extracted from the heart a Senile Systemic Amyloidosis Patient |
7z40 | CryoEM |
residues:11-35, 57-123 | resolution:2.78 |
|  |  |
---|
|
336 △ | Transthyretin |
Steinebrei et al., 2022 |
Human, wild type, extracted from the heart a Senile Systemic Amyloidosis Patient |
8ade | CryoEM |
residues:11-35, 57-123 | resolution:2.78 |
|  |  |
---|
|
337 △ | Transthyretin |
Nguyen et al., 2023 |
Human, wild type, extracted from the heart a Transthyretin Amyloidosis Patient |
8e7d | CryoEM |
residues:11-34, 58-123 | resolution:3.31 |
|  |  |
---|
|
338 △ | Transthyretin |
Nguyen et al., 2023 |
Human, wild type, extracted from the heart a Transthyretin Amyloidosis Patient |
8e7h | CryoEM |
residues:12-35, 58-123 | resolution:3.7 |
|  |  |
---|
|
339 △ | Transthyretin, I84S |
Nguyen et al., 2023 |
Human, I84S mutation, extracted from the heart a Transthyretin Amyloidosis Patient |
8e7e | CryoEM |
residues:14-32, 67-122 | resolution:3.61 |
|  |  |
---|
|
340 △ | Transthyretin, I84S |
Nguyen et al., 2023 |
Human, I84S mutation, extracted from the heart a Transthyretin Amyloidosis Patient |
8e7j | CryoEM |
residues:12-35, 64-122 | resolution:3.1 |
|  |  |
---|
|
| Protein Information | Polarity Map | Energy Map |
---|
341 △ | Transthyretin, P24S |
Nguyen et al., 2023 |
Human, P24S mutation, extracted from the heart a Transthyretin Amyloidosis Patient |
8e7i | CryoEM |
residues:12-34, 58-123 | resolution:3.65 |
|  |  |
---|
|
342 △ | Transthyretin, V30M |
Schmidt et al., 2019 |
Human, V30M mutation, extracted from heart of a patient with hereditary V30M ATTR Amyloidosis |
6sdz | cryoEM |
residues:11-35, 57-123 | resolution:3 |
|  |  |
---|
|
343 △ | Transthyretin, V30M |
Iakovleva et al., 2021 |
Human, V30M mutation, extracted from the eye of an Amyloid Transthyretin Amyloidosis (ATTR) Patient |
7ob4 | CryoEM |
residues:11-35, 57-123 | resolution:3.22 |
|  |  |
---|
|